Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

This study has suspended participant recruitment.
Sponsor:
Information provided by:
University Hospital, Ghent
ClinicalTrials.gov Identifier:
NCT00117416
First received: June 30, 2005
Last updated: December 19, 2007
Last verified: December 2007
  Purpose

The purpose of this study is to evaluate the renal perfusion depending on the MAP.


Condition Intervention
Kidney Failure, Acute
Procedure: controlling the MAP

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: MAP and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

Resource links provided by NLM:


Further study details as provided by University Hospital, Ghent:

Primary Outcome Measures:
  • creatinine clearance after 4 hours

Secondary Outcome Measures:
  • resistance index
  • diuresis
  • urinary indices of renal function

Estimated Enrollment: 60
Study Start Date: February 2003
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Over 18 years old
  • Intensive care patient
  • Treated with vasopressor
  • Given informed consent
  • Arterial infusion
  • A bladder catheter

Exclusion Criteria:

  • Anamneses of hypertension
  • Neurological trauma
  • Acute renal insufficiency other than prerenal or acute tubular necrosis etiology
  • Hepatorenal syndrome
  • Treated with diuretics
  • Mechanical ventilation and unstable
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00117416

Locations
Belgium
University Hospital Ghent
Ghent, Belgium, 9000
Sponsors and Collaborators
University Hospital, Ghent
Investigators
Principal Investigator: Eric Hoste, MD, PhD University Hospital, Ghent
  More Information

Additional Information:
No publications provided

ClinicalTrials.gov Identifier: NCT00117416     History of Changes
Other Study ID Numbers: 2002/382
Study First Received: June 30, 2005
Last Updated: December 19, 2007
Health Authority: Belgium: Federal Agency for Medicines and Health Products, FAMHP

Additional relevant MeSH terms:
Renal Insufficiency
Critical Illness
Acute Kidney Injury
Kidney Diseases
Urologic Diseases
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on October 01, 2014