Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

This study has suspended participant recruitment.
Sponsor:
Information provided by:
University Hospital, Ghent
ClinicalTrials.gov Identifier:
NCT00117416
First received: June 30, 2005
Last updated: December 19, 2007
Last verified: December 2007
  Purpose

The purpose of this study is to evaluate the renal perfusion depending on the MAP.


Condition Intervention
Kidney Failure, Acute
Procedure: controlling the MAP

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: MAP and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function

Resource links provided by NLM:


Further study details as provided by University Hospital, Ghent:

Primary Outcome Measures:
  • creatinine clearance after 4 hours

Secondary Outcome Measures:
  • resistance index
  • diuresis
  • urinary indices of renal function

Estimated Enrollment: 60
Study Start Date: February 2003
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Over 18 years old
  • Intensive care patient
  • Treated with vasopressor
  • Given informed consent
  • Arterial infusion
  • A bladder catheter

Exclusion Criteria:

  • Anamneses of hypertension
  • Neurological trauma
  • Acute renal insufficiency other than prerenal or acute tubular necrosis etiology
  • Hepatorenal syndrome
  • Treated with diuretics
  • Mechanical ventilation and unstable
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00117416

Locations
Belgium
University Hospital Ghent
Ghent, Belgium, 9000
Sponsors and Collaborators
University Hospital, Ghent
Investigators
Principal Investigator: Eric Hoste, MD, PhD University Hospital, Ghent
  More Information

Additional Information:
No publications provided

ClinicalTrials.gov Identifier: NCT00117416     History of Changes
Other Study ID Numbers: 2002/382
Study First Received: June 30, 2005
Last Updated: December 19, 2007
Health Authority: Belgium: Federal Agency for Medicines and Health Products, FAMHP

Additional relevant MeSH terms:
Critical Illness
Acute Kidney Injury
Renal Insufficiency
Disease Attributes
Pathologic Processes
Kidney Diseases
Urologic Diseases

ClinicalTrials.gov processed this record on April 17, 2014