Patient Centered Communication Training to Reduce Antibiotic Use in Acute Respiratory Tract Infections

This study has been completed.
Sponsor:
Collaborators:
Basel Institute of Clinical Epidemiology (BICE)
Swiss National Science Foundation
Novartis
Information provided by:
University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier:
NCT00105248
First received: March 10, 2005
Last updated: December 7, 2005
Last verified: March 2005
  Purpose

The purpose of this study is to evaluate the effectiveness of a short training program for general practitioners in patient-centered communication to reduce antibiotic prescription for acute respiratory tract infections (ARTI).


Condition Intervention
Respiratory Tract Infections
Behavioral: patient-centered communication training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Educational/Counseling/Training
Official Title: Multidimensional Intervention Program to Reduce Antibiotic Prescriptions for Acute Respiratory Tract Infections in Adults: a Randomized Controlled Trial in Primary Care

Resource links provided by NLM:


Further study details as provided by University Hospital, Basel, Switzerland:

Primary Outcome Measures:
  • Up-take of antibiotic prescription confirmed by pharmacists within 2 weeks following the initial consultation

Secondary Outcome Measures:
  • Patient satisfaction with consultation (on validated scale)
  • patient enablement (on validated scale)
  • days with restriction from ARTI within 14 days initial consultation
  • side effects from medication
  • re-consultation rates
  • days off from work

Estimated Enrollment: 900
Study Start Date: January 2004
Estimated Study Completion Date: June 2004
Detailed Description:

Acute respiratory tract infections (ARTI) constitute the most frequent reason for seeking ambulatory care and for the prescription of antibiotics, despite the mostly viral origin of ARTI. Antibiotic prescriptions for ARTI increase unnecessary drug expenditures and are the main reason for increasing drug resistance of common bacteria. Evidence from intervention studies shows that merely providing physicians with guidelines and educational material for the management of acute respiratory tract infections is not enough to reduce antibiotic prescriptions for these conditions. The main reasons for antibiotic prescription in ARTI are non-medical and related to the physician patient relationship, patients’ expectations and beliefs about the benefit of antibiotics. Therefore patient-centered communication could be a promising approach to reduce the rate of antibiotic prescription in ambulatory care.

Comparison: General practitioners (GPs) trained in patient-centered communication in addition to evidence-based guidelines for diagnosis and treatment of ARTI compared to GPs just introduced to evidence-based guidelines.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • 18 years or older
  • Symptoms of an acute respiratory tract infection for >1 and <28 days

Exclusion Criteria:

  • Patients without informed consent
  • Not fluent in German
  • Patients with a psychiatric disorder
  • Patients with a recurrent respiratory system infection with antibiotic treatment in the previous 4 weeks
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00105248

Locations
Switzerland
Basel institute for clinical epidemiology
Basel, Switzerland, 4031
Sponsors and Collaborators
University Hospital, Basel, Switzerland
Basel Institute of Clinical Epidemiology (BICE)
Swiss National Science Foundation
Novartis
Investigators
Principal Investigator: Heiner Bucher, Prof. University Hospital, Basel, Switzerland
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00105248     History of Changes
Other Study ID Numbers: 3200B0-102137, 04B29, 2003/051, 242/03
Study First Received: March 10, 2005
Last Updated: December 7, 2005
Health Authority: Switzerland: Swissmedic

Keywords provided by University Hospital, Basel, Switzerland:
acute repiratory infections
antibiotic therapy
patient-centred communication
randomized controlled trial

Additional relevant MeSH terms:
Respiratory Tract Infections
Infection
Respiratory Tract Diseases
Anti-Bacterial Agents
Antibiotics, Antitubercular
Anti-Infective Agents
Therapeutic Uses
Pharmacologic Actions
Antitubercular Agents

ClinicalTrials.gov processed this record on July 28, 2014