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Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome

This study has been completed.
Sponsor:
Information provided by:
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00100425
First received: December 30, 2004
Last updated: January 20, 2009
Last verified: December 2004
History of Changes
  Purpose

The purpose of this study is to provide new information and to determine which kinds of brief, tolerable, experimental pain are affected by the drugs being studied in patients with irritable bowel syndrome, a disease that causes chronic abdominal pain. The effects of dextromethorphan, naloxone, and fentanyl on experimental pain stimuli will be tested in these studies to better understand what causes irritable bowel syndrome.


Condition Intervention
Irritable Bowel Syndrome
 Procedure: Viceral Perception Testing

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Double-Blind
Primary Purpose: Diagnostic
Official Title: Central Nervous System Modulation of Visceral Pain in Persian Gulf War Syndrome

Further study details as provided by Department of Veterans Affairs:

Study Start Date: September 2000
  Eligibility

Ages Eligible for Study:   18 Years to 72 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria
  • Patients with irritable bowel syndrome and healthy pain-free individuals (as controls) will be studied.
  • No medical condition that would contraindicate use of dextromethorphan, fentanyl or naloxone.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00100425

Locations
United States, Florida
Malcolm Randall VA Medical Center
Gainesville, Florida, United States, 32608
Sponsors and Collaborators
Department of Veterans Affairs
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00100425     History of Changes
Other Study ID Numbers: CADE-ARCD2
Study First Received: December 30, 2004
Last Updated: January 20, 2009
Health Authority: United States: Federal Government

Keywords provided by Department of Veterans Affairs:
Irritable Bowel Syndrome
Visceral Hypersensitivity
Visceral Pain

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Persian Gulf Syndrome
Colonic Diseases, Functional
Colonic Diseases
 Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Occupational Diseases

ClinicalTrials.gov processed this record on May 16, 2013