A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain
This study has been completed.
Information provided by:
First received: September 22, 2004
Last updated: January 21, 2010
Last verified: January 2010
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
Drug: MK0966, rofecoxib
Drug: Comparator: valdecoxib, placebo
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
|Official Title:||A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effects of Rofecoxib 50 mg and Valdecoxib 40 mg in Patients With Postoperative Dental Pain|
Resource links provided by NLM:
Further study details as provided by Merck:
Primary Outcome Measures:
- Overall analgesic effect as measured by total pain relief over 12 hours.
Secondary Outcome Measures:
- Overall analgesic effect over 8 hrs.
- Time to onset of analgesic, peak analgesic and duration of analgesic effects.
- Percent of patients using and amount used of supplemental analgesia within 8, 12, and 24 hrs.
- Overall safety and tolerability.
|Study Start Date:||August 2002|
The duration of treatment is 1 day.
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