A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain
This study has been completed.
Information provided by:
First received: September 22, 2004
Last updated: January 21, 2010
Last verified: January 2010
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
Drug: MK0966, rofecoxib
Drug: Comparator: oxycodone and acetaminophen
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
|Official Title:||A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Study to Evaluate the Efficacy of Rofecoxib and a Dosing Regimen of Oxycodone With Acetaminophen Over 24 Hours in Patients With Postoperative Dental Pain|
Resource links provided by NLM:
Further study details as provided by Merck:
Primary Outcome Measures:
- Post-op dental pain over 6 hours as measured by pain intensity/relief scores, patient global assessment, and time to perceptible/meaningful pain relief.
Secondary Outcome Measures:
- Time to onset of analgesic effect, peak analgesic effect, and/or duration of analgesic effect over 24 hours.
|Study Start Date:||June 2002|
|Study Completion Date:||September 2002|
|Primary Completion Date:||September 2002 (Final data collection date for primary outcome measure)|
The duration of treatment is 24 hours.
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