Community-Based Cognitive Therapy for Suicide Attempters - Full Text View

Sponsor:	National Institute of Mental Health (NIMH)
Information provided by:	National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:	NCT00081367

Purpose

This study will determine the effectiveness of cognitive behavioral therapy (CBT) in preventing future suicide attempts in repeat suicide attempters.

Condition	Intervention	Phase
Suicide, Attempted	Behavioral: CBT Behavioral: Standard care alone	Phase III

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment
Official Title:	Community-Based Cognitive Therapy for Suicide Attempters

Resource links provided by NLM:

MedlinePlus related topics: Suicide

U.S. FDA Resources

Further study details as provided by National Institute of Mental Health (NIMH):

Primary Outcome Measures:

Repeat suicide attempts [ Time Frame: Measured during treatment and 1, 3, 6, 12, 18, and 24 months after study completion ] [ Designated as safety issue: Yes ]

Estimated Enrollment:	120
Estimated Study Completion Date:	September 2009
Estimated Primary Completion Date:	September 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Cognitive behavioral therapy (CBT) plus standard care	Behavioral: CBT Participants will receive ten weekly sessions of treatment. Suicidal thoughts or attempts, hopelessness, depression, health care utilization, and overall psychological and social adaptation will be assessed. Behavioral: Standard care alone Participants will receive standard care for suicide prevention.
Active Comparator: Standard care alone	Behavioral: Standard care alone Participants will receive standard care for suicide prevention.

Detailed Description:

Rates of mental health and substance use disorders are high among economically disadvantaged, ethnic minority populations. Studies have shown that CBT designed for this high-risk population is successful at reducing suicide attempts in people with suicidal thoughts or attempts. This study will implement a CBT intervention into the community and will focus on increasing compliance with psychiatric, substance abuse, and medical treatment.

Participants in this study will be randomly assigned to receive either CBT plus standard care or standard care alone. Participants who receive CBT will have ten weekly sessions of treatment. Suicidal thoughts or attempts, hopelessness, depression, health care utilization, and overall psychological and social adaptation will be assessed. Assessments will be made 1, 3, 6, 12, 18, and 24 months after study completion.

Eligibility

Ages Eligible for Study:	16 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Suicide attempt within 48 hours prior to being evaluated at the hospital
English speaking
Able to provide 2 verifiable contacts

Exclusion Criteria:

Acute, unstable, or severe Axis III disorder or a severe Axis I disorder that may prevent safe participation in outpatient psychotherapy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00081367

Locations

United States, Pennsylvania
University of Pennsylvania - Psychopathology Research Unit
Philadelphia, Pennsylvania, United States, 19104

Sponsors and Collaborators

National Institute of Mental Health (NIMH)

More Information

Publications:

Brown GK, Ten Have T, Henriques GR, Xie SX, Hollander JE, Beck AT. Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial. JAMA. 2005 Aug 3;294(5):563-70.

Responsible Party:	Aaron T. Beck , MD, University of Pennsylvannia Medical School
ClinicalTrials.gov Identifier:	NCT00081367 History of Changes
Other Study ID Numbers:	R01 MH67805, DSIR 83-ATP
Study First Received:	April 9, 2004
Last Updated:	October 5, 2010
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Mental Health (NIMH):

Minority Groups

Additional relevant MeSH terms:

Suicide
Suicide, Attempted
Self-Injurious Behavior
Behavioral Symptoms

ClinicalTrials.gov processed this record on February 12, 2012