High Intensity Light Therapy in Alzheimer's Disease

This study has been completed.
Sponsor:
Information provided by:
National Center for Complementary and Alternative Medicine (NCCAM)
ClinicalTrials.gov Identifier:
NCT00065689
First received: July 31, 2003
Last updated: July 24, 2006
Last verified: July 2006
  Purpose

The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the best timing for the light therapy. The light levels being used in the study have been shown to improve depression in persons with seasonal affective disorder (SAD) and to relieve sleep problems in persons with jet lag and other body rhythm disturbances. Because persons with AD often will not remain still in front of a fluorescent panel, this project has involved renovations in the study units that provide for even, regulated, high-intensity light in all public areas of the study settings.


Condition Intervention Phase
Alzheimer's Disease
Dementia
Device: high-intensity light therapy
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind
Primary Purpose: Treatment
Official Title: High Intensity Light Therapy in Alzheimer's Disease

Resource links provided by NLM:


Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):

Estimated Enrollment: 107
Study Start Date: March 2003
Estimated Study Completion Date: September 2005
Detailed Description:

See Brief Summary

  Eligibility

Ages Eligible for Study:   55 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • Diagnosis of dementia
  • Residence on study units

Exclusion criteria:

  • Bipolar disorder
  • Severe retinal (eye) disease
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00065689

Locations
United States, North Carolina
John Umstead Hospital
Butner, North Carolina, United States, 27514
Sponsors and Collaborators
Investigators
Principal Investigator: Philip D. Sloane, MD, MPH
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00065689     History of Changes
Other Study ID Numbers: R01 AT000212-01A1, SloaneP
Study First Received: July 31, 2003
Last Updated: July 24, 2006
Health Authority: United States: Federal Government

Keywords provided by National Center for Complementary and Alternative Medicine (NCCAM):
Alzheimer's disease
light therapy
long-term care
depression
sleep
agitation

Additional relevant MeSH terms:
Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on July 20, 2014