Effectiveness of Binge Eating Disorder Treatments

This study has been completed.
Sponsor:
Information provided by:
National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:
NCT00060762
First received: May 12, 2003
Last updated: November 7, 2008
Last verified: November 2008
  Purpose

This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).


Condition Intervention Phase
Eating Disorders
Behavioral: Interpersonal Therapy
Behavioral: Behavioral Weight Loss Treatment
Behavioral: Guided Self Help
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Effectiveness of Psychological Treatments for BED

Resource links provided by NLM:


Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment: 210
Study Start Date: April 2002
Estimated Study Completion Date: March 2005
Detailed Description:

BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED.

Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • DSM-IV criteria for Binge Eating Disorder
  • Body Mass Index (BMI) between 27 and 45
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00060762

Locations
United States, California
W. Stewart Agras
Stanford, California, United States, 94305
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63100
United States, New Jersey
Rutgers University Eating Disorder Clinic
Piscataway, New Jersey, United States, 08854
Sponsors and Collaborators
  More Information

No publications provided by National Institute of Mental Health (NIMH)

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: W. Stewart Agras, Stanford University
ClinicalTrials.gov Identifier: NCT00060762     History of Changes
Other Study ID Numbers: R01 MH63863, DSIR 83-ATAS
Study First Received: May 12, 2003
Last Updated: November 7, 2008
Health Authority: United States: Federal Government

Keywords provided by National Institute of Mental Health (NIMH):
Weight Loss

Additional relevant MeSH terms:
Eating Disorders
Binge-Eating Disorder
Mental Disorders

ClinicalTrials.gov processed this record on April 21, 2014