Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Treatment for Depression in the Primary Care Setting

This study has been completed.
Sponsor:
Collaborator:
Information provided by:
Dartmouth-Hitchcock Medical Center
ClinicalTrials.gov Identifier:
NCT00055328
First received: February 25, 2003
Last updated: September 6, 2013
Last verified: August 2008
  Purpose

This study will compare a brief form of counseling to usual care for the treatment of minor depression in the primary care setting.


Condition Intervention Phase
Depression
Behavioral: Problem-Solving Treatment for Primary Care
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Problem-Solving Treatment for Primary Care Depression

Further study details as provided by Dartmouth-Hitchcock Medical Center:

Estimated Enrollment: 300
Study Start Date: December 2002
Study Completion Date: December 2006
Detailed Description:

Minor depression is one of the most common types of depressive disorders seen in primary care. The effectiveness and tolerability of antidepressants in patients with minor depression is unclear, and the development of alternative treatments is necessary.

In the first phase of this study, participants are observed for 4 weeks to identify those most in need of depression-specific treatment. Participants are then exposed to the Problem-Solving Treatment for Primary Care (PST-PC), a six-session behavioral treatment for depression. After 4 weeks, patients who do not respond adequately to the treatment are randomly assigned to either continued PST-PC or to usual care for 9 weeks. Participants are followed for 6 months after the study.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Primary care patient at Dartmouth-Hitchcock Medical Center (DHMC)
  • Hamilton Depression Score >= 10 and minor depression at time of entry and after 4 weeks of observation

Exclusion Criteria:

  • Psychosis, Obsessive Compulsive Disorder (OCD), or Post Traumatic Stress Disorder (PTSD)
  • Active substance abuse
  • Receiving treatment for depression
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00055328

Locations
United States, New Hampshire
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Sponsors and Collaborators
Dartmouth-Hitchcock Medical Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00055328     History of Changes
Other Study ID Numbers: R01 MH62322, R01MH062322, DATR A4-GPS
Study First Received: February 25, 2003
Last Updated: September 6, 2013
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mental Disorders
Mood Disorders

ClinicalTrials.gov processed this record on November 25, 2014