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Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease

This study has been completed.
Sponsor:
Information provided by:
Eli Lilly and Company
ClinicalTrials.gov Identifier:
NCT00051909
First received: January 17, 2003
Last updated: July 18, 2006
Last verified: July 2006
History of Changes
  Purpose

Study of an investigational medication for the treatment of Alzheimer's Disease in patients who are not taking Aricept, Reminyl, Exelon.


Condition Intervention Phase
Alzheimer's Disease
 Drug: LY451395
 Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Eli Lilly and Company:

Estimated Enrollment: 200
Study Start Date: November 2002
Estimated Study Completion Date: June 2003
  Eligibility

Ages Eligible for Study:   50 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Must have a clinical diagnosis of Alzheimer's Disease
  • Must be at least 50 years of age
  • Must fluently read and speak English
  • Must have a reliable caregiver

Exclusion Criteria:

  • Has serious health problems other than Alzheimer's Disease
  • Cannot swallow whole pills
  • Has had a menstrual period in the last two years
  • Takes insulin for diabetes
  • Has taken Aricept, Reminyl, or Exelon in the last 5 weeks
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00051909

Locations
United States, California
Beverly Hills, California, United States
Fresno, California, United States
United States, Florida
Boca Raton, Florida, United States
Fort Lauderdale, Florida, United States
Miami Beach, Florida, United States
United States, Massachusetts
Boston, Massachusetts, United States
United States, Oklahoma
Oklahoma City, Oklahoma, United States
Tulsa, Oklahoma, United States
United States, Texas
Wichita Falls, Texas, United States
Sponsors and Collaborators
Eli Lilly and Company
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00051909     History of Changes
Other Study ID Numbers: 6764, H6N-MC-LEAM
Study First Received: January 17, 2003
Last Updated: July 18, 2006
Health Authority: United States: Food and Drug Administration

Keywords provided by Eli Lilly and Company:
Alzheimer's Disease

Additional relevant MeSH terms:
Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
 Tauopathies
Neurodegenerative Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 22, 2013