St. John’s Wort Vs. Placebo in Obsessive-Compulsive Disorder.
The purpose of this study is to determine the effectiveness of St. John’s Wort as compared to placebo (an inactive substance) in the treatment of outpatients with obsessive compulsive disorder.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||St. John’s Wort Vs. Placebo in Obsessive-Compulsive Disorder.|
|Study Start Date:||May 2002|
|Estimated Study Completion Date:||September 2003|
The objective of the proposed study is to assess the efficacy of the herbal St. John’s Wort (SJW) in the treatment of symptoms of obsessive-compulsive disorder (OCD). The approach is to conduct a 12-week, randomized, double blind, placebo controlled, parallel group pilot trial with 30 subjects in each of two arms. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) will be the primary measure for evaluating OCD. An intention-to-treat analysis will be done to compare the two arms.
|United States, Oklahoma|
|University of Oklahoma Health Science Center|
|Oklahoma City, Oklahoma, United States, 73190|
|United States, Wisconsin|
|Madison, Wisconsin, United States, 53562|
|Principal Investigator:||Kenneth Kobak, PhD||Dean Foundation for Health, Research and Analysis|
|Principal Investigator:||Leslie Taylo, MD||Dean Foundation for Health, Research and Analysis|