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Environmental Contaminants and Infant Development

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2001 by National Institute of Environmental Health Sciences (NIEHS).
Recruitment status was  Recruiting
Sponsor:
Collaborators:
Indian and Northern Affairs, Canada
Health Canada
Danish Institute for Public Health
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00013858
First received: March 30, 2001
Last updated: June 23, 2005
Last verified: February 2001
History of Changes
  Purpose

This study is designed to examine the effects of prenatal exposure to environmental contaminants on cognitive and behavioral development and physical growth in two groups of Inuit infants-one in Northern Quebec; the other in Greenland.


Condition
Mercury Poisoning
Lead Poisoning

Study Type: Observational
Study Design: Additional Descriptors: Psychosocial
Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Estimated Enrollment: 280
Study Start Date: January 1997
Estimated Study Completion Date: December 2002
Detailed Description:

Due to prevailing weather patterns and ocean currents, certain environmental contaminants are transported to the Arctic region. The Inuit are among the most heavily exposed populations on earth due to the prevalence of these contaminants in traditional foods that comprise a large portion of their diet. The contaminants assessed in this study include polychlorinated biphenyls (PCBs), methylmercury, selenium, organochlorine pesticides, and lead. These contaminants are measured in umbilical cord blood samples obtained at birth, milk samples obtained from breast-feeding mothers and, in the case of mercury, hair samples obtained from the mothers. Omega-3 and omega-6 fatty acids are also assessed in these samples to examine the degree to which these nutrients may protect against adverse effects attributable to these contaminants.

  Eligibility

Ages Eligible for Study:   up to 1 Day
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

infant born during recruitment period to a mother who is a resident of Povungnituk, Inukjuak, and Kuujjuarapik, Quebec or Nuuk, Greenland

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00013858

Contacts
Contact: Joseph L Jacobson, Ph.D. 313-577-2802 jljacobson@yahoo.com

Locations
Canada, Quebec
Public Health Centre of Quebec Recruiting
Beauport, Quebec, Canada
Contact: Gina Muckle, Ph.D.     418-666-7000 ext 360     gina.muckle@crchul.ulaval.ca    
Principal Investigator: Joseph L Jacobson, Ph.D.            
Sponsors and Collaborators
National Institute of Environmental Health Sciences (NIEHS)
Indian and Northern Affairs, Canada
Health Canada
Danish Institute for Public Health
  More Information

Publications:
Dewailly, E., Bruneau, S., Ayotte, P., Liliberte, C., Gingras, S. Belander, D. and Ferron, L. Health status at birth of Inuit newborn prenatally exposed to organochlorines - Chemosphre, 1993, 27: 359-366.

ClinicalTrials.gov Identifier: NCT00013858     History of Changes
Other Study ID Numbers: 7902-CP-001
Study First Received: March 30, 2001
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
methylmercury
PCBs
lead
fish consumption
breast-feeding

Additional relevant MeSH terms:
Lead Poisoning
Mercury Poisoning
Poisoning
Substance-Related Disorders

ClinicalTrials.gov processed this record on June 18, 2013