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Exposure, Dose, Body Burden and Health Effects of Lead

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2002 by National Institute of Environmental Health Sciences (NIEHS).
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00013819
First received: March 29, 2001
Last updated: June 23, 2005
Last verified: July 2002
History of Changes
  Purpose

This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.


Condition
Lead Poisoning

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by National Institute of Environmental Health Sciences (NIEHS):

Estimated Enrollment: 944
Study Start Date: February 1997
Estimated Study Completion Date: February 2002
  Eligibility

Ages Eligible for Study:   17 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Lead workers in South Korea in one of 26 specific lead-using facilities.

Population controls in South Korea.

  Contacts and Locations
No Contacts or Locations Provided
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00013819     History of Changes
Other Study ID Numbers: 7198-CP-001
Study First Received: March 29, 2001
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):
lead poisoning
central nervous system
peripheral nervous system
occupational health
genetic susceptibility

Additional relevant MeSH terms:
Lead Poisoning
Poisoning
Substance-Related Disorders

ClinicalTrials.gov processed this record on May 19, 2013