Study of Topical Calcitriol in Children With Psoriasis
I. Determine the therapeutic efficacy and safety of topical calcitriol in children with psoriasis.
|Study Design:||Primary Purpose: Treatment|
|Study Start Date:||July 2000|
|Estimated Study Completion Date:||July 2000|
PROTOCOL OUTLINE: Patients apply topical calcitriol in petrolatum on a psoriatic lesion daily. Patients also apply petrolatum without calcitriol to another psoriatic lesion daily.
Patients have both lesions photographed prior to therapy, monthly during therapy, and at the completion of therapy. Lesions are assessed weekly for 1 month and then every 2 weeks while on study. Blood samples are collected every 1 to 2 months and urine samples are collected every 2 weeks while on study.
|Study Chair:||Michael F. Holick||Boston University|