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The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2001 by National Center for Research Resources (NCRR).
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:
NCT00005923
First received: June 23, 2000
Last updated: June 23, 2005
Last verified: November 2001
History of Changes
  Purpose

The proposed research is an observational study designed to compare estrogen and progesterone serum levels with knee and ankle joint laxity, and muscle reaction time as a measure of neuromuscular function. Three groups of women athletes with differing estrogen and progesterone profiles (normal menstrual cycles, amenorrheic, and exogenous estrogen supplementation) and one control group (male collegiate athletes) will be used to compare differences in joint laxity and neuromuscular function. Blood levels of estrogen and progesterone will be measured at four time points across the menstrual cycle. Joint laxity and muscle reaction time will also be measured at each of these points. The investigator hypothesizes that knee and ankle joint laxity and muscle reaction time will significantly increase with increasing estrogen and progesterone levels.


Condition
Healthy

Study Type: Observational
Study Design: Observational Model: Natural History

Further study details as provided by National Center for Research Resources (NCRR):

  Eligibility

Ages Eligible for Study:   15 Years to 23 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • pre-collegiate or collegiate athletes
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00005923

Locations
United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05405
Sponsors and Collaborators
National Center for Research Resources (NCRR)
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00005923     History of Changes
Other Study ID Numbers: NCRR-M01RR00109-0749, M01RR00109
Study First Received: June 23, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
Joint Instability

ClinicalTrials.gov processed this record on May 19, 2013