Multi-Ethnic Study of Atherosclerosis (MESA)
This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005487
First received: May 25, 2000
Last updated: April 26, 2012
Last verified: April 2012
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Purpose
To conduct a prospective observational study of the characteristics of subclinical cardiovascular disease (disease detected non-invasively before it has produced signs and symptoms) that predict progression to clinically overt cardiovascular disease in a diverse and representative population-based sample of men and women aged 35-84. Specifically the study shall: determine characteristics related to progression of subclinical to clinical cardiovascular disease; identify factors related to newer measures of subclinical disease and examine relationship of new to established measures; and develop population-based methods, suitable for application in future screening and intervention studies, for identifying asymptomatic persons at highest risk of clinical events.
| Condition |
|---|
|
Atherosclerosis Cardiovascular Diseases Heart Diseases Coronary Artery Disease Coronary Disease Stroke Myocardial Infarction Heart Failure Diabetes Mellitus, Type 2 Hypertension Diabetes Mellitus |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Multi-Ethnic Study of Atherosclerosis (MESA) |
Resource links provided by NLM:
MedlinePlus related topics:
Atherosclerosis
Coronary Artery Disease
Diabetes
Diabetes Type 2
Heart Attack
Heart Diseases
Heart Failure
High Blood Pressure
U.S. FDA Resources
Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):
| Estimated Enrollment: | 6000 |
| Study Start Date: | January 1999 |
| Estimated Study Completion Date: | August 2015 |
| Estimated Primary Completion Date: | August 2015 (Final data collection date for primary outcome measure) |
Show Detailed Description Eligibility| Ages Eligible for Study: | 45 Years to 84 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Participants were recruited from the MESA Study Field Centers.
Criteria
No eligibility criteria
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00005487
Sponsors and Collaborators
Investigators
| Principal Investigator: | David Bluemke | Johns Hopkins University |
| Principal Investigator: | Gregory Burke | Wake Forest University |
| Principal Investigator: | Aaron Folsom | University of Minnesota - Clinical and Translational Science Institute |
| Principal Investigator: | Richard Kronmal | University of Washington |
| Principal Investigator: | Kiang Liu | Northwestern University |
| Principal Investigator: | Daniel O'Leary | New England Medical Center Hospitals |
| Principal Investigator: | Steven Shea | Columbia University |
| Principal Investigator: | Moyses Szklo | Johns Hopkins University |
| Principal Investigator: | Russell Tracy | University of Vermont |
| Principal Investigator: | Matthew Budoff | Los Angeles Biomedical Research Institute |
| Principal Investigator: | Karol Watson | University of California, Los Angeles |
More Information
Additional Information:
Publications:
Auchincloss AH, Diez Roux AV, Brown DG, Erdmann CA, Bertoni AG. Associations between insulin resistance and resources for physical activity and healthy foods: the Multi-Ethnic Study of Atherosclerosis. Epidemiology. (In press)
Ding J, Kritchevsky SB, Harris TB, Burke GL, Detrano RC, Szklo M, Carr J. The association of pericardial fat with calcified coronary plaque: The Multi-Ethnic Study of Atherosclerosis. Obesity. (In press)
Han C, Kronmal R. Two-part models for analysis of Agatston scores with possible proportionality constraints. Communications in Statistics-Theory and Methods. 2006;35(1):99-111.
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | National Heart, Lung, and Blood Institute (NHLBI) |
| ClinicalTrials.gov Identifier: | NCT00005487 History of Changes |
| Other Study ID Numbers: | 5003 |
| Study First Received: | May 25, 2000 |
| Last Updated: | April 26, 2012 |
| Health Authority: | United States: Federal Government |
Keywords provided by National Heart, Lung, and Blood Institute (NHLBI):
|
Coronary Arteriosclerosis Cerebrovascular Accident Heart Failure, Congestive Diabetes Mellitus, Non-Insulin Dependent |
Additional relevant MeSH terms:
|
Atherosclerosis Cardiovascular Diseases Coronary Artery Disease Myocardial Ischemia Coronary Disease Diabetes Mellitus Diabetes Mellitus, Type 2 Heart Diseases Heart Failure Hypertension Infarction Myocardial Infarction Stroke |
Arteriosclerosis Arterial Occlusive Diseases Vascular Diseases Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases Ischemia Pathologic Processes Necrosis Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases |
ClinicalTrials.gov processed this record on May 19, 2013