Indices of Severity and Prognosis for Sickle Cell Disease
This study has been completed.
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005467
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: May 2000
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Purpose
To develop a clinical severity index that could prospectively identify sickle cell disease patients who were at high risk for a turbulent clinical course and a poor prognosis.
| Condition |
|---|
|
Anemia, Sickle Cell Blood Disease |
| Study Type: | Observational |
| Study Design: | Observational Model: Natural History |
Resource links provided by NLM:
Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):
| Study Start Date: | January 1990 |
| Estimated Study Completion Date: | December 1992 |
DESIGN NARRATIVE:
Using the database, univariate analysis showed that factors associated with the occurrence of cerebrovascular accident (51 patients) included hematocrit, rate of change of pocked red cell count, and polymer fraction at 40 percent oxygen saturation (PF40). Only low hematocrit was predictive of death in the pediatric cohort. There were 45 disease-related deaths.
Eligibility| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Criteria
No eligibility criteria
Contacts and Locations
No Contacts or Locations Provided
More Information
Publications:
| ClinicalTrials.gov Identifier: | NCT00005467 History of Changes |
| Other Study ID Numbers: | 4912 |
| Study First Received: | May 25, 2000 |
| Last Updated: | June 23, 2005 |
| Health Authority: | United States: Federal Government |
Additional relevant MeSH terms:
|
Anemia Anemia, Sickle Cell Hematologic Diseases Anemia, Hemolytic, Congenital |
Anemia, Hemolytic Hemoglobinopathies Genetic Diseases, Inborn |
ClinicalTrials.gov processed this record on May 16, 2013