Behavioral Factors in Coronary Heart Disease

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Duke University
ClinicalTrials.gov Identifier:
NCT00005314
First received: May 25, 2000
Last updated: February 3, 2014
Last verified: February 2014
  Purpose

To elucidate the role of biobehavioral factors in the etiology, pathogenesis and course of coronary heart disease (CHD) and to use this knowledge to devise more effective prevention, treatment and rehabilitation approaches.


Condition
Cardiovascular Diseases
Heart Diseases
Coronary Disease
Metabolic Syndrome X

Study Type: Observational
Study Design: Observational Model: Family-Based
Time Perspective: Cross-Sectional

Resource links provided by NLM:


Further study details as provided by Duke University:

Primary Outcome Measures:
  • Manifestations of the metabolic syndrome [ Time Frame: Ongoing ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Urine and plasma samples and extracted DNA are retained


Enrollment: 694
Study Start Date: July 1986
Estimated Study Completion Date: March 2015
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   22 Years to 45 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Healthy normal volunteers

Criteria

We will recruit 500 probands (half African American and half Caucasian, half men and half women, and half scoring in the top and half in the bottom 20% on an established hostility scale), at least one sibling from each proband and as many parents as possible.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00005314

Sponsors and Collaborators
Duke University
Investigators
Principal Investigator: Redford B Williams, M.D. Duke University
  More Information

Publications:

Responsible Party: Duke University
ClinicalTrials.gov Identifier: NCT00005314     History of Changes
Other Study ID Numbers: Pro00008338, P01HL036587
Study First Received: May 25, 2000
Last Updated: February 3, 2014
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Metabolic Syndrome X
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on August 01, 2014