Familial Aggregation and Natural History of Sleep Apnea

This study has been completed.
Information provided by (Responsible Party):
Susan Redline, Brigham and Women's Hospital
ClinicalTrials.gov Identifier:
First received: May 25, 2000
Last updated: July 29, 2013
Last verified: July 2013

To quantify the influence of genetic and environmental factors on the development of sleep apnea.

Lung Diseases
Sleep Apnea Syndromes

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Brigham and Women's Hospital:

Primary Outcome Measures:
  • Sleep Apnea [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Samples stored deidentified

Enrollment: 726
Study Start Date: August 1990
Study Completion Date: March 2008
Primary Completion Date: March 2008 (Final data collection date for primary outcome measure)
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Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Probands with sleep apnea and family members; neighborhood control families


sleep apnea, or family member or neighbor of proband

  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00005299

Sponsors and Collaborators
Brigham and Women's Hospital
Principal Investigator: Susan Redline Case Western Reserve University
Principal Investigator: Susan Redline, MD Brigham and Women's Hospital
  More Information


Responsible Party: Susan Redline, Professor, Brigham and Women's Hospital
ClinicalTrials.gov Identifier: NCT00005299     History of Changes
Other Study ID Numbers: 2022, R01HL046380-15
Study First Received: May 25, 2000
Last Updated: July 29, 2013
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Lung Diseases
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Sleep Disorders
Nervous System Diseases

ClinicalTrials.gov processed this record on October 19, 2014