Tucson Epidemiology Study of Chronic Obstructive Lung Diseases

This study has been completed.
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005279
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: May 2002
  Purpose

To determine the natural history, etiology, and interrelationships of emphysema, chronic bronchitis, asthma, and related airways obstructive diseases. Also, to determine the relationship of acute lower respiratory tract illnesses in infants and children to the development of subsequent chronic lung disorders.


Condition
Asthma
Bronchitis
Emphysema
Lung Diseases, Obstructive
Chronic Obstructive Pulmonary Disease

Study Type: Observational

Resource links provided by NLM:


Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: June 1971
Estimated Study Completion Date: November 1997
  Show Detailed Description

  Eligibility

Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

No eligibility criteria

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Publications:
Burrows B (Ed): Chronic Respiratory Disease, Med Clin North Am, W.B. Saunders Co, May 1973
Burrows B: Prognosis of the Bronchial and Emphysematous Types. In: Chron Obstr Lung, Stuttgart: Schattauer, pp. 171-173, 1975
Lebowitz M: Aerosol Usage and Respiratory Symptomatology. Arch Environ Health. (Presented at Food and Drug Administration Hearings, Washington, D.C, Dec. 16-18, 1974
Barbee R, Lebowitz MD, Morse JO, Burrows B: The Relationships of Atopy and Smoking Habits to Respiratory Disease in a General Population. (Abs) J Clin Res, 24:121A, 1976
Taussig L, Lebowitz MD: Cough and Wheeze Syndromes in Children. (abs) Am Rev Respir Dis, 113 (part 2):45, 1976
Lebowitz MD: A Critical Examination of Factorial Ecology and Social Area Analysis for Epidemiological Research. J Az Acad Sci, 12:86-90, 1977
Lebowitz MD, Johnson WM, Kaltenborn W: Coccidioidin Skin Test Reactivity and Cross-Reactivity with Histoplasmin in a Tucson Population. Coccidioidomycosis (Ajello, L, Ed.) Selected Papers from 3rd Intr. Coccidioidomycosis Symposium, Tucson, Az., Nov, 1976, Miami, Fla.: Symposia Specialists 1977
Lebowitz MD: Alcohol Consumption, Smoking and Respiratory Symptomatology. (abs) Am J Epidemiol, 106:248, 1977 (Presented at the 10th Annual Meeting Soc. Epidemiol Res., Seattle, June 16, 1977
Lebowitz MD, Knudson RJ, Armet D, Kaltenborn W, Burrows B: Longitudinal Changes in Lung Function and Respiratory Symptoms. (abs) IEA Proc, 1977, 193 (Presented at the 8th Scientific Meeting of IEA, San Juan, Puerto Rico September 1977
Morse JO, Lebowitz MD, Knudson RJ: Value of Antitrypsin Screening. (Correspondence) N Engl J Med, 297:454-455, 1977
Lebowitz MD: Temporal Analysis of Acute Respiratory Symptoms, Aero-Allergens and Air Pollution. (abs) IEA Proc., 194 (Presented at the 8th Scientific Meeting of IEA, San Juan, Puerto Rico, September 1977
Burrows B: Course and Prognosis in Advanced Disease. In: Chronic Obstructive Pulmonary Disease, Petty T (Ed), New York: Marcel Dekker, Inc., Chapter 2, pp. 23-33, 1978
Garfield M, Sugihara S, Abraham TA, Lebowitz MD, Burrows B: Characteristics of Individuals With Rapidly Declining FEV1 Identified Within a General Population. (abs) Am Rev Respir Dis, 121(#4, part 2):138, 1980. Presented at the ATS Annual Meeting, Washington, D.C., May 21, 1980
Abraham TA, Garfield M, Sugihara S, Lebowitz MD, Burrows B: Methacholine Inhalation Challenge in Normal Individuals Using the Maximum and Partial Flow Curves With an Assessment of Diurnal Variation. (abst) Am Rev Respir Dis, 121 (#4, Part 2):53, 1980
Burrows B: Prognostic Factors in Chronic Obstructive Pulmonary Disease. Pract Cardiol, 6(10):61-69, 1980
Wagener JS, Taussig LM, Burrows B, Hernried L, Boat T: Comparison of Lung Function and Survival Patterns Between Cystic Fibrosis and Emphysema or Chronic Bronchitis Patients. Perspectives in Cystic Fibrosis, Proceedings of the 8th International Cystic Fibrosis Congress, Toronto, May 1980
Lebowitz MD: Potential Surveillance: Respiratory Indicators. Environ Res, 25:225-235, 1981
Lebowitz MD: Epidemiological Recognition of Occupational Pulmonary Disease. In: Clinics in Chest Medicine. W.B. Saunders Company: Philadelphia. 2(#3):305-316, 1981
Frank R, Lebowitz MD: The Risk of Staying In. (Editorial) Am Rev Respir Dis, 124:522, 1981
Landau LI, Taussig LM, Burrows B, Cline M, Lebowitz MD, Knudson R: Sex Differences in Growth Velocity of Lung Function Assessed From Longitudinal Measurements in Healthy Subjects Age 6 to 25 Years. Australian Ped J, 17(2):145, 1981
Dodge R, Burrows B: Chronic Bronchitis and Emphysema. In: Prognosis Contemporary Outcomes of Disease. (JF Fries, GE Ehrlich, Eds) Bowie, MD: Charles Press Publishers, pp. 228-231, 1981
Burrows B: Introduction to Symposium on Pulmonary Disorders. Postgrad Medicine, 69:100-101, 1981
Burrows B: Management of Chronic Obstructive Lung Disease. Drug Ther, pp. 127-133, Nov. 1981
Coaker L, Lebowitz MD, Abraham T, Garfield M, Suqihara S, Burrows B: Methacholine Challenge: The Correlation of Smoking With Airway Response in Symptomatic and Asymptomatic Subjects. Am Rev Respir Dis, 125(#4, part 2):253, 1982
Lebowitz MD, Knudson RJ, Armet D, Kaltenborn W, Burrows B: Smoking and Longitudinal Changes in Lung Function and Respiratory Symptoms. Indian J Chest Dis, Special Number: Smoking and Health, pp. 47-56, 1982
Burrows B: Irreversible Airways Obstruction and Asthma. Pract Cardiol, 8(7):69-81, 1982
Lebowitz MD, Armet DB, Knudson RJ: The Effect of Passive Smoking on Pulmonary Function in Children. Environ Internat'l, 8:371-374, 1982
Lebowitz MD: The Effects of Alcohol Ingestion on the Lung. Pract Cardiol, 8:101-104, 1982
Lebowitz M, O'Rourke M, Dodge R, Holberg C, Corman G, Hoshaw R, Pinnas J, Barbee R, Sneller M: The Adverse Health Effects of Biological Aerosols, Other Aerosols, and Microclimate Indoors on Asthmatics and Non-Asthmatics. Environ Internat'l, 8:375-380, 1982
Burrows B: The Natural History of Airflow Limitation. Med Clin North Am, pp. 2157-2162, April 1982
Burrows B: The Natural History of Airflow Limitation. Med Internat'l, 1:955-956, 1982
Lebowitz MD, Dodge R, Holberg C: The Effects of the Environment on Pulmonary Function in Children, In: Proceedings of the National Congress on Pediatric Bronchopneumonology. D. Castello (Ed), Turin: Italian Ped. Bronchopneumonal. Assn., 1982
Bloom, JW, Sugihara S, Garfield M, Abraham T, Knudson RJ: Factors Associated With Rapid Decline in Lung Function. Am Rev Respir Dis, 125:258S, 1982
Lebowitz MD: Health Effects of Indoor Pollution. Ann Rev Public Health, 4:203-221, 1983
Bloom J, Sugihara S, Garfield M, Abraham T, Knudson RJ: Characteristics of Individuals With Accelerated Declines in Lung Function. Chest, 85(6):18S-19S, 1983
Lebowitz MD: Toxic Substances in the Atmospheric Environment: A Discussion. J Air Polln Control Assn, 33(9):832-834, 1983
Lebowitz MD, Dodge RR, Holberg CJ, Corman G, Boyer B: Daily Symptoms Related to Indoor Pollution in Adult Asthmatics and Non-Asthmatics. Am J Epidemiol, 118(3):419, 1983
Burrows B: COPD: A New Look at DX and RX of an Old Problem. Modern Med, pp. 114-126, March, 1983
Burrows B, Knudson RJ, Quan SF, Kettel LJ: Respiratory Disorders: A Pathophysiologic Approach, 2nd Ed. Revised. Chicago: Year Book Medical Publishers, Inc. 1983
Burrows B: Early Diagnosis of COPD: Value of Annual Spirometric Examination of Smokers. Pract Cardiol, 9:143-150, 1983
Burrows B: Trends in Respiratory Medicine. Todays Therapeutic Trends, 1:11-20, 1983
Sobonya RE, Burrows B: The Epidemiology of Emphysema. Clin Chest Med, 4:351-358, 1983
Lebowitz MD: Potential Respiratory Problems Within the Home Environment, In: Energy, Air Pollution and Health: Seminar Proceedings. W. Linn (Ed) New York: American Lung Association, pp. 76-87, 1983
Lebowitz MD, Waller RE, Jacobsen M, Kostrezewski J, Hasegawa Y (Eds): Guidelines on Studies in Environmental Epidemiology. (Environmental Health Criteria 27) Geneva: World Health Organization, 1983
Lebowitz MD, et al: Organization and Conduct of Studies. Chapter 5 in: Lebowitz MD, Waller RE, Jacobsen M, Kostrezewski J, Hasegawa Y, (Eds) Guidelines on Studies in Environmental Epidemiology. (Environmental Health Criteria 27) Geneva: World Health Organization, pp. 211-261, 1983
Bloom JW, Farland AM, Halonen M, Burrows B: Pneumococcus Specific IgE in Cigarette Smokers. Am Rev Respir Dis, 129(4):A191, 1984
Lebowitz MD, Knudson R, Burrows B: Risk Factors for Airway Obstructive Diseases: A Multiple Logistics Approach. Chest, 85(6):11S-12S, 1984
Bloom JW, Burrows B: Diseases Associated With Airflow Limitation, In: Current Pulmonology, Vol. 5 (Simmons DH, Ed) John Wiley & Sons, Inc., pp. 255-281, 1984
Burrows B: Possible Pathogenetic Mechanisms in Chronic Airflow Obstruction. Chest, 85S:13S-15S, 1984
Camilli A, Paoletti P, Lebowitz MD: Types of Occupational Exposures, Respiratory Symptoms and Lung Function. Am Rev Respir Dis, 129 (#4, part 2):A170, 1984
Dodge RR, Lebowitz MD, Barbee RA, Burrows B: Immediate Reactions to Coccidioidin and Spherulin: The Relation of Atopy to Coccidioidomycosis. In: Einstein H (Ed), Coccidioidomycosis: Proceedings of the Fourth International Conference, Washington, DC: Nat'l Foundation Infectious Diseases, 1985
Martinez F, Lebowitz MD, Taussig LM: A Longitudinal Study on the Outcome of Asthmatic Syndromes in Infancy and Childhood. Am Rev Respir Dis, 131(#4, part 2):A243, 1985
Holberg CJ, O'Rourke MK, Lebowitz MD: A Factor For All Seasons. Am Rev Respir Dis, 131 (#4, part 2):A176, 1985
Lebowitz MD: Prevalence and Natural History of Asthma. In 'Lessons From the Past' (Reed C, Ed) Bernstein IL (Ed) Guidelines for Evaluation of Nonbronchodilator Therapy of Asthma. Wash., DC: American Academy of Allergy and Immunology, pp. 8-22, 1986
Lebowitz MD: Passive Smoking and Health Effects. In IAQ, Stockholm: Liber Tryk, 6:29-32, 1986
Barbee RA: The Epidemiology of Asthma. Chapter in Monograph on Epidemiology of Allergic Diseases, Schlumberger HD (Ed). S Karger, Basel, Publisher. 1987
Lebowitz MD, Quackenboss JJ, et al: Development of Questionnaires and Survey Instruments. In: Design and Protocol. Phila.: ASTM, (in press), 1987
Lebowitz MD: Respiratory Symptom: Concepts and Techniques for the Study of Respiratory Changes in Aging. In: Kent B and Butler RN (Eds), Human Aging Research: Concepts and Techniques. New York: Raven Press, 1988
Lebowitz MD: Prevalence and Incidence Rates of Airway Obstructive Peroblems: An International Comparison. Med Thoracica, 10:189-93, 1988
Lebowitz MD: Allergy Sufferers in the Southwest. Medical and Health Annual Chicago: Encyclopedia Britannica, pp. 274-276, 1988
Burrows B: Distribution of Allergy in the General Population. In: Bronchits IV. Proceedings Royal Van Gorcum Assen. The Netherlands. pp. 3-13, 1989
Burrows B: Allergy and Its Relationship to Asthma, Bronchial Reactivity and Chronic Airways Obstruction: An Epidemiological Perspective. In: S.T. Weiss and D. Sparrow (Eds), Airways Responsiveness and Allergy in the Development of Chronic Lung Disease. Raven Press, New York, NY, pp. 241-270, 1989
Barbee RA: Airways Responsiveness and Allergy in the Development of Chronic Lung Disease. In: Methodological Issues in the Assessment of Allergy. Edited by ST Weiss, M.D. and D Sparrow, M.D. Raven Press, New York, 1989
Burrows B: Natural History of Chronic Airflow Obstruction. In: Clinical Epidemiology of Chronic Obstructive Pulmonary Disease (Eds) M Hensley and NA Saunders. Marcel Dekker, Inc., 1989
Sieber OF Jr, Lucas DL, Lohman C, Larter W, Giles H, John TJ: Reactivity of Lymphocytes in Maternal and Cord Blood to Respiratory Syncytial Virus. Clin Res, XXIV, 181A, 1976
Strunk RC, Sieber OF Jr, Taussig LM, Gall EP: Serum Complement Depression Associated With Viral Pulmonary Illness in Cystic Fibrosis. Clin Res, XXIV, 198A, 1976
Sieber OF Jr: Relationships Between the Allergic State and Susceptibility to Infectious Airway Disease. Pediatr Res, 11:230, 1977
Morgan WJ, Taussig LM: Chronic Bronchitis. Pediatric Clinics of North America -- The Pediatric Airway. W. B. Saunders Co. August, 1984
Carroll J, Taussig LM: Pulmonary Disorders. In: Immunologic Disorders in Infants and Children. Stiehm ER (Ed). W. B. Saunders Co. Edition III, 1985
Mellins R, Chernick V, Clyde W, Farrell P, Glezen WP, Rigatto H, Taussig LM: Pediatric Respiratory Disorders. NIH Publication #86-2107 August 1986
Morgan WJ: Evaluation of Forced Expiratory Flow in Infants. Proceedings of the Second State of the Art Conference on Neonatal Pulmonary Function Testing, Chicago, Perinatology Press, Ithaca, NY, 1988
Neddenriep D, Taussig LM: Infection of the Lower Respiratory Tract. In: Enchenwald, HF (Ed), Current Therapy in Pediatrics, 2, B.C. Decker Co, 1989
Summut PH, Taussig LM: Cystic Fibrosis in the Adolescent and Adult. In: Current Pulmonolgy, Vol. 10, Year Book Medical Publishers, 1989
Grad R, Taussig LM: Acute Infections Producing Upper Airway Obstruction. In: Chernick, V (Ed): Disorders of the Respiratory Tract in Children, 5th Ed., Saunders Co., 1989
Habib MP, Burrows B : Chronic Airways Obstruction: The Importance of Certain Risk Factors for Its Development. In: Current Pulmonology. DH Simmons (Ed), Year Book Medical Publishers, 1989.

ClinicalTrials.gov Identifier: NCT00005279     History of Changes
Other Study ID Numbers: 2000
Study First Received: May 25, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Asthma
Bronchitis
Emphysema
Pulmonary Emphysema
Lung Diseases
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Bronchial Diseases
Respiratory Tract Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Respiratory Tract Infections
Pathologic Processes

ClinicalTrials.gov processed this record on August 28, 2014