Speech Characteristics in Coronary Heart Disease

This study has been completed.
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005157
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: May 2000
  Purpose

To improve the predictive validity of Structured Interview assessments of Type A behavior by comparing interviewer techniques in the Multiple Risk Factor Intervention Trial (MRFIT) and the Western Collaborative Group Study (WCGS). To assess whether there were interviewer differences in the predictiveness of Type A behavior and its components for coronary heart disease incidence in MRFIT and WCGS and if so, to assess whether the interviewer differences in disease predictiveness were related to interviewer stylistics.


Condition
Cardiovascular Diseases
Heart Diseases
Coronary Disease

Study Type: Observational
Study Design: Observational Model: Natural History

Resource links provided by NLM:


Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: July 1982
Estimated Study Completion Date: November 1989
Detailed Description:

BACKGROUND:

Individuals with Type A behavior are characterized as hard driving, competitive, and time urgent; when asked questions they are quick to answer with emphatic speech; they perceive themselves to be striving and competing and are prone to hostility. This core of behaviors is presumed to be on a continuum of intensity with well-developed Type A's at the upper end and well-developed Type B's at the lower end. Epidemiological studies have shown Type A's to have a higher prevalence and incidence of various forms of coronary heart disease than Type B's. The Structured Interview is a method of measuring Type A behavior in which a series of questions are administered about the individual's characteristic responses to situations relevant to the Type A behavior pattern, such as reaction to delay and reported frequency of anger. The Interview is delivered in challenging style designed to elicit Type A characteristics.

In 1960, the WCGS recruited 3,154 employed men, ages 39 to 59, who were initially free of coronary heart disease and followed them for 8.5 years for coronary heart disease incidence. In 1972 MRFIT began recruiting 12,866 men, ages 35 to 57, selected for elevation of one or more risk factors, but free from coronary heart disease and followed them for an average of seven years after randomization to a risk factor modification group or to a control group referred to their own physicians for treatment. Both studies used the Structured Interview to assess Type A behavior.

In 1981, Type A behavior was officially regarded as an independent risk factor for coronary heart disease, based largely on the findings of the WCGS. However, the MRFIT did not find Type A behavior to be related to coronary heart disease incidence. The manner of conducting the Structured Interview may have affected the predictive reliability of the Type A assessments.

DESIGN NARRATIVE:

Interviewer speech characteristics from the WCGS and MRFIT Structured Interview tape recordings were audited and analyzed. Each speech characteristic was scored with high reliability. Multiple logistic regression analyses were used to control for standard risk factors.

  Eligibility

Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

No eligibility criteria

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Publications:
Scherwitz L, Graham L, Ornish D: Self-Involvement and the Risk Factors for Coronary Heart Disease. Advances, Institute for the Advancement of Health. Vol 2:6-18, 1985
Scherwitz L, Canick J: Self-Reference and Coronary Heart Disease Risk. In: Houston K & Snyder CR (Eds.), Type A Behavior Pattern: Research, Theory, and Intervention. John Wiley & Sons, New York, 1987
Scherwitz L: Interviewer Behaviors in the Western Collaborative Group Study and the Multiple Risk Factor Intervention Trial Structured Interviews. In: Houston K & Snyder CR (Eds.), Type A Behavior Pattern: Research, Theory, and Intervention. John Wiley & Sons, New York, 1987
Scherwitz L: Type A Behavior Assessment in the Structured Interview: Review, Critique, and Recommendations. In: Siegman A (Ed.), In Search of Coronary-Prone Behavior. Lawrence Erlbaum, Hillsdale, NJ, 1987

ClinicalTrials.gov Identifier: NCT00005157     History of Changes
Other Study ID Numbers: 1029
Study First Received: May 25, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Cardiovascular Diseases
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases

ClinicalTrials.gov processed this record on July 26, 2014