Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Chronic Inflammatory Demyelinating Polyneuropathy
I. Compare the response of previously untreated patients with chronic inflammatory demyelinating polyneuropathy to intravenous immune globulin vs. placebo.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Drug: Immune globulin
|Study Design:||Allocation: Randomized
Primary Purpose: Treatment
|Study Start Date:||September 1992|
PROTOCOL OUTLINE: This is a randomized, double-blind study. The first group receives intravenous immune globulin (IVIG) on days 1, 2, and 21; the second group receives an intravenous placebo on the same schedule.
Patients in either group may receive IVIG (same dosage as first group) after day 42.
Concurrent steroids and other immune globulin preparations are prohibited.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004772
|Study Chair:||Jerry R. Mendell||Ohio State University|