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Genetic Linkage Study for Hereditary Pancreatitis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2006 by Office of Rare Diseases (ORD).
Recruitment status was  Recruiting
Sponsor:
Collaborator:
University of Pittsburgh
Information provided by:
Office of Rare Diseases (ORD)
ClinicalTrials.gov Identifier:
NCT00004475
First received: October 18, 1999
Last updated: September 5, 2006
Last verified: September 2006
History of Changes
  Purpose

OBJECTIVES:

I. Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene.


Condition Intervention
Pancreatitis
 Procedure: genetic testing

Study Type: Observational
Study Design: Observational Model: Natural History

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Office of Rare Diseases (ORD):

Study Start Date: December 1998
Detailed Description:

PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients and family members. DNA is extracted from the blood and used for genotypic analysis and linkage analysis.

Patients do not necessarily receive the results of the genetic testing and the results do not influence the type or duration of treatment.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria
  • Diagnosis of hereditary pancreatitis with confirmation of phenotype by: Onset of pain before age 20 Amylase elevation at least 2 times normal Surgical or postmortem confirmation of pancreatitis Unequivocal evidence of pancreatic exocrine insufficiency in the absence of trauma, alcohol abuse, elevated serum lipids, or other known causes
  • Family member of a patient diagnosed with hereditary pancreatitis
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004475

Locations
United States, Pennsylvania
University of Pittsburgh, Presbyterian University Hospital Recruiting
Pittsburgh, Pennsylvania, United States, 15213-2582
Contact: David C. Whitcomb     412-648-9115        
Contact: Beth D. Elinoff     888-748-8362     elinoffb@msx.dept-med.pitt.edu    
Sponsors and Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Pittsburgh
Investigators
Study Chair: David C. Whitcomb University of Pittsburgh
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00004475     History of Changes
Other Study ID Numbers: 199/14042, UPMC-951061, UPMC-R01DK54709-01, UPMC-R03DK51954
Study First Received: October 18, 1999
Last Updated: September 5, 2006
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Pancreatitis
Pancreatitis, Chronic
Pancreatic Diseases
Digestive System Diseases

ClinicalTrials.gov processed this record on June 18, 2013