Immune System Related Kidney Disease

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2014 by National Institutes of Health Clinical Center (CC)
Sponsor:
Information provided by:
National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:
NCT00001979
First received: January 20, 2000
Last updated: March 14, 2014
Last verified: February 2014
  Purpose

Kidney diseases related to the immune system include, nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with connective tissue disorders.

This study will allow researchers to admit and follow patients suffering from autoimmune diseases of the kidney. It will attempt to provide information about the causes and specific abnormalities associated with autoimmune kidney disease.

Patients with kidney disease as a result of their immune system, and patients with diseases of the immune system who may later develop kidney disease, will be potential subjects for this study.

Patients will undergo a history and physical examination, and standard laboratory test to more closely understand the causes, signs, symptoms, and responses to medication of these diseases. Based on these evaluations the patients may qualify as candidates for other experimental studies. At any time these patients may be asked to submit blood or urine samples for further research.


Condition
Glomerulonephritis
Lupus Nephritis
Membranous Glomerulonephritis
Nephritis
Nephrotic Syndrome

Study Type: Observational
Official Title: Studies of Immunologically-Mediated Kidney Diseases

Resource links provided by NLM:


Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment: 99999999
Study Start Date: April 1992
Detailed Description:

Patients with known or suspected immunologically-mediated kidney diseases, including but not limited to, nephritic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with other systemic or connective tissue disorders, will be evaluated at the Clinical Center. Patients who have immunologically-mediated diseases with potential for kidney disease will be evaluated as well. Studies will include characterization of the clinical and laboratory features of these disorders, studies of natural history and complications, evaluation of responses to standard treatment, and determination of the patients' eligibility to enter other experimental diagnostic or therapeutic protocols. Patients may be asked to contribute blood and/or urine samples for immunological research studies.

  Eligibility

Ages Eligible for Study:   5 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria
  • INCLUSION CRITERIA:

Immunologically-mediated renal diseases, proven or suspected.

Immunologically-mediated diseases with potential for kidney disease.

Willingness of the patient or guardian to give informed consent.

EXCLUSION CRITERIA:

Concomitant medical problems which would confound the interpretation of studies of the immunologic kidney disorder.

Concomitant medical, surgical or other conditions for which inadequate facilities or funds are available to support their care at the NIH.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001979

Contacts
Contact: Howard A Austin, M.D. (301) 435-5055 howarda@intra.niddk.nih.gov

Locations
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)    800-411-1222 ext TTY8664111010    prpl@mail.cc.nih.gov   
Sponsors and Collaborators
Investigators
Principal Investigator: Howard A Austin, M.D. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  More Information

Additional Information:
Publications:
ClinicalTrials.gov Identifier: NCT00001979     History of Changes
Other Study ID Numbers: 920156, 92-DK-0156
Study First Received: January 20, 2000
Last Updated: March 14, 2014
Health Authority: United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Glomerulonephritis
Nephropathy
Lupus
Nephritis
Nephrotic Syndrome

Additional relevant MeSH terms:
Glomerulonephritis
Glomerulonephritis, Membranous
Kidney Diseases
Lupus Nephritis
Nephritis
Nephrotic Syndrome
Syndrome
Autoimmune Diseases
Connective Tissue Diseases
Disease
Immune System Diseases
Lupus Erythematosus, Systemic
Nephrosis
Pathologic Processes
Urologic Diseases

ClinicalTrials.gov processed this record on October 20, 2014