Diagnosing and Treating Low Blood Sugar Levels

This study is currently recruiting participants.

Verified May 2011 by National Institutes of Health Clinical Center (CC)

First Received on November 3, 1999. Last Updated on December 24, 2011 History of Changes

Sponsor:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001276

Purpose

Hypoglycemia is the term used to refer to lower than normal levels of blood sugar. This study will continue to research the causes of hypoglycemia.

Patients involved in the study will be admitted to the Clinical Center of the National Institutes of Health and undergo tests for evaluating blood sugar. Patients will be required to refrain from eating for a set period of time and will undergo blood tests for insulin levels and several other specific diagnostic tests related to insulin secretion. The patients will be under supervision and will be provided with appropriate medical and surgical attention as needed.

Condition
Hypoglycemia Insulinoma

Study Type:	Observational
Official Title:	Fasting Hypoglycemia: Diagnosis and Treatment

Resource links provided by NLM:

MedlinePlus related topics: Diabetes Medicines Hypoglycemia

U.S. FDA Resources

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment:	99999999
Study Start Date:	January 1991

Detailed Description:

The purpose of this protocol is to continue our studies of the evaluation and treatment of patients with fasting hypoglycemia due to diverse etiologies. Patients will be admitted to the Clinical Research Center under this protocol and undergo supervised fasting, dynamic tests of insulin secretion when appropriate, medically indicated imaging studies, and appropriate medical and surgical treatment.

Eligibility

Ages Eligible for Study:	10 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

INCLUSION CRITERIA

Documentation of plasma glucose below 45 mg/dl is required for enrollment.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001276

Contacts

Contact: Patient Recruitment and Public Liaison Office	(800) 411-1222	prpl@mail.cc.nih.gov
Contact: TTY	1-866-411-1010

Locations

United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike	Recruiting
Bethesda, Maryland, United States, 20892
Sub-Investigator: Patient Recruitment and Public Liaison Office (PRPL) For more information at the NIH Clinical Center contact

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

More Information

Additional Information:

NIH Clinical Center Detailed Web Page This link exits the ClinicalTrials.gov site

Publications:

Bar RS, Gorden P, Roth J, Siebert CW. Insulin receptors in patients with insulinomas: changes in receptor affinity and concentration. J Clin Endocrinol Metab. 1977 Jun;44(6):1210-3.

Blackshear PJ, Rotner HE, Kriauciunas KA, Kahn CR. Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus. Ann Intern Med. 1983 Aug;99(2):182-4.

Comi RJ, Gorden P. Approach to hypoglycemia in adults. Compr Ther. 1987 Mar;13(3):38-44. No abstract available.

ClinicalTrials.gov Identifier:	NCT00001276 History of Changes
Other Study ID Numbers:	910066, 91-DK-0066
Study First Received:	November 3, 1999
Last Updated:	December 24, 2011
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Hypoglycemia
Insulinoma

Additional relevant MeSH terms:

Hypoglycemia
Insulinoma
Glucose Metabolism Disorders
Metabolic Diseases
Adenoma, Islet Cell
Adenoma
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type

Neoplasms
Pancreatic Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Endocrine Gland Neoplasms
Digestive System Diseases
Pancreatic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on February 12, 2012