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| Sponsor: | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
|---|---|
| Information provided by: | National Institutes of Health Clinical Center (CC) |
| ClinicalTrials.gov Identifier: | NCT00001159 |
Purpose
Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, Graves' Dermopathy, and thyroid-stimulating hormone (TSH) secreting pituitary adenomas.
The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of thyroid function disorders. Many of the tests performed are in the context of standard medical care that is offered to all patients with thyroid function disorders. In addition, blood and tissue samples may be taken for research and genetic studies.
| Condition |
|---|
|
Hyperthyroidism Hypothyroidism Pituitary Neoplasm |
| Study Type: | Observational |
| Official Title: | Evaluation of Patients With Thyroid Function Disorders |
| Estimated Enrollment: | 99999999 |
| Study Start Date: | January 1977 |
Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied and
treated in this protocol. A limited number of patients with a personal history of signs, symptomsor laboratory studies consistent with thyroid dysfunction or a strong family history of thyroid abnormalities are also enrolled. Patients undergo routine history and physical examination, standard endocrine blood and urine tests, a standard TRH test, thyroid nuclear medicine scans, thyroidal radioiodine (RAI) or technetium (99mTc) uptake measurements, as well as X-ray, computed tomography (CT) or magnetic resonance imaging (MRI) studies or other standard diagnostic procedures, as clinically indicated. Patients will be screened for entry into other research studies.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Patients of any age with known or suspected thyroid abnormalities may be included in this study. These disorders can be broadly defined as hyper- or hypothyroid states and laboratory abnormalities.
Contacts and Locations| Contact: Patient Recruitment and Public Liaison Office | (800) 411-1222 | prpl@mail.cc.nih.gov |
| Contact: TTY | 1-866-411-1010 |
| United States, Maryland | |
| National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
| Bethesda, Maryland, United States, 20892 | |
| Sub-Investigator: Patient Recruitment and Public Liaison Office (PRPL) For more information at the NIH Clinical Center contact | |
More Information
| ClinicalTrials.gov Identifier: | NCT00001159 History of Changes |
| Other Study ID Numbers: | 770002, 77-DK-0002 |
| Study First Received: | November 3, 1999 |
| Last Updated: | February 3, 2012 |
| Health Authority: | United States: Federal Government |
|
Thyroid Pituitary Tumors Hormone Resistance Hyperthyroidism |
Hypothyroidism Thyroid-Stimulating Hormone Secreting Pituitary Adenomas TSH Secreting Pituitary Adenomas Graves' Dermopathy |
|
Neoplasms Hyperthyroidism Hypothyroidism Pituitary Neoplasms Thyroid Diseases Endocrine System Diseases Endocrine Gland Neoplasms Neoplasms by Site Hypothalamic Neoplasms |
Supratentorial Neoplasms Brain Neoplasms Central Nervous System Neoplasms Nervous System Neoplasms Brain Diseases Central Nervous System Diseases Nervous System Diseases Hypothalamic Diseases Pituitary Diseases |