Serotonin/Dopamine Antagonism of Cocaine Effect: 1 - 1

This study has been terminated.

First Received on September 20, 1999. Last Updated on June 23, 2005 History of Changes

Sponsor:	National Institute on Drug Abuse (NIDA)
Collaborator:	VA Boston Healthcare System
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000309

Purpose

The purpose of this study is to evaluate use of risperidone with cocaine abusers. Study measures incorporate an appropriate integration of behavioral and neurobiological indices.

Condition	Intervention	Phase
Cocaine-Related Disorders	Drug: Risperidone	Phase II

Study Type:	Interventional
Study Design:	Allocation: Randomized Masking: Double-Blind Primary Purpose: Treatment
Official Title:	Serotonin/Dopamine Antagonism of Cocaine Effect

Resource links provided by NLM:

Drug Information available for: Serotonin Dopamine Cocaine hydrochloride Dopamine hydrochloride Risperidone

U.S. FDA Resources

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Analog mood scales
POMS
EPS sx

Estimated Enrollment:	0
Study Start Date:	August 1994

Eligibility

Ages Eligible for Study:	18 Years to 50 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000309

Locations

United States, Rhode Island
Brown University School of Medicine
Providence, Rhode Island, United States, 2906

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

VA Boston Healthcare System

Investigators

Principal Investigator:

Lawrence Price, M.D.

Brown University

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00000309 History of Changes
Other Study ID Numbers:	NIDA-09330-1, R01-09330-1
Study First Received:	September 20, 1999
Last Updated:	June 23, 2005
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Cocaine-Related Disorders
Substance-Related Disorders
Mental Disorders
Dopamine
Risperidone
Serotonin
Cardiotonic Agents
Cardiovascular Agents
Therapeutic Uses
Pharmacologic Actions
Sympathomimetics
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs

Dopamine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Protective Agents
Serotonin Receptor Agonists
Serotonin Agents
Serotonin Antagonists
Antipsychotic Agents
Tranquilizing Agents
Central Nervous System Depressants
Central Nervous System Agents
Psychotropic Drugs
Dopamine Antagonists

ClinicalTrials.gov processed this record on February 12, 2012