Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8

This study has been completed.

First Received on September 20, 1999. Last Updated on October 5, 2011 History of Changes

Sponsor:	University of Chicago
Collaborator:	National Institute on Drug Abuse (NIDA)
Information provided by:	University of Chicago
ClinicalTrials.gov Identifier:	NCT00000256

Purpose

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine reinforcing effects of brief exposures to nitrous oxide in healthy volunteers.

Condition	Intervention	Phase
Opioid-Related Disorders Substance-Related Disorders	Drug: Nitrous oxide	Phase II

Study Type:	Interventional
Study Design:	Primary Purpose: Treatment
Official Title:	Reinforcing Effects of Brief Exposures to Nitrous Oxide

Resource links provided by NLM:

MedlinePlus related topics: Drug Abuse

Drug Information available for: Nitrous oxide

U.S. FDA Resources

Further study details as provided by University of Chicago:

Primary Outcome Measures:

Mood

Estimated Enrollment:	0
Study Start Date:	August 1995

Eligibility

Ages Eligible for Study:	22 Years to 34 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000256

Locations

United States, Illinois
University of Chicago, Anesthesia & Critical Care
Chicago, Illinois, United States, 60637

Sponsors and Collaborators

University of Chicago

National Institute on Drug Abuse (NIDA)

Investigators

Principal Investigator:

James Zacny, Ph.D.

University of Chicago

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00000256 History of Changes
Other Study ID Numbers:	NIDA-08391-8, R01DA008391, R01-08391-8
Study First Received:	September 20, 1999
Last Updated:	October 5, 2011
Health Authority:	United States: Federal Government

Additional relevant MeSH terms:

Opioid-Related Disorders
Substance-Related Disorders
Mental Disorders
Nitrous Oxide
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents

Physiological Effects of Drugs
Pharmacologic Actions
Central Nervous System Agents
Therapeutic Uses
Anesthetics, Inhalation
Anesthetics, General
Anesthetics
Central Nervous System Depressants

ClinicalTrials.gov processed this record on February 12, 2012