88 studies found for:    topeka | Open Studies
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21 Available Expanded Treatment Protocol With LDK378 in ALK(+) NSCLC
Condition: Non-small Cell Lung Cancer (NSCLC)
Intervention: Drug: LDK378
22 Recruiting Long-Term Study Of CP-690,550 In Subjects With Ulcerative Colitis
Condition: Ulcerative Colitis
Intervention: Drug: CP-690,550
23 Recruiting A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, Both With Insulin Aspart as Mealtime Insulin in Subjects With Type 1 Diabetes
Conditions: Diabetes;   Diabetes Mellitus, Type 1
Interventions: Drug: insulin degludec;   Drug: insulin glargine;   Drug: insulin aspart
24 Recruiting A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: fluticasone furoate (FF);   Drug: vilanterol (VI);   Drug: umeclidinium bromide (UMEC)
25 Recruiting Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)
Conditions: Vaso-occlusive Crisis;   Sickle Cell Disease
Interventions: Drug: MST-188;   Drug: Saline
26 Recruiting Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes
Conditions: Diabetes;   Diabetes Mellitus, Type 2
Interventions: Drug: liraglutide;   Drug: placebo;   Drug: metformin
27 Recruiting A Study of the Safety and Effectiveness of LY3053102 in Participants With Type 2 Diabetes
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: LY3053102;   Drug: Exenatide extended release;   Drug: Placebo
28 Recruiting Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)
Condition: Venous Thromboembolism (VTE)
Interventions: Drug: Betrixaban;   Drug: Enoxaparin
29 Recruiting Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer
Condition: Hormone Receptor Positive Breast Cancer
Interventions: Drug: Everolimus;   Drug: Letrozole;   Drug: Exemestane;   Drug: Alcohol-free dexamethasone mouth rinse
30 Recruiting A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: LY2944876;   Drug: Exenatide extended-release;   Drug: Placebo
31 Recruiting S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma
Conditions: Lymphoma;   Nonneoplastic Condition
Interventions: Biological: bleomycin sulfate;   Biological: filgrastim;   Drug: ABVD regimen;   Drug: BEACOPP regimen;   Drug: cyclophosphamide;   Drug: dacarbazine;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: prednisone;   Drug: procarbazine hydrochloride;   Drug: vinblastine sulfate;   Drug: vincristine sulfate
32 Recruiting A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza
Condition: Influenza, Human
Interventions: Drug: 300mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 600mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 75mg oral oseltamivir and intravenous zanamivir placebo
33 Recruiting TR-701 FA vs Linezolid for the Treatment of Nosocomial Pneumonia
Condition: Pneumonia
Interventions: Drug: TR-701 FA IV;   Drug: Linezolid
34 Not yet recruiting Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction
Condition: Chronic Heart Failure With Reduced Ejection Fraction.
Intervention: Drug: LCZ696
35 Recruiting Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes
Condition: Type 2 Diabetes
Interventions: Drug: placebo;   Drug: exenatide
36 Recruiting A Global Study to Assess the Effects of MEDI4736 in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer
Intervention: Drug: MEDI4736
37 Recruiting Randomized On-X Anticoagulation Trial
Condition: Heart Valve Disease
Interventions: Device: On-X valve using reduced anticoagulation;   Device: On-X Valve with Standard Coumadin Therapy
38 Recruiting Efficacy and Safety of Anti-MAP Therapy in Adult Crohn's Disease
Condition: Crohn's Disease
Interventions: Drug: RHB-104;   Drug: Placebo
39 Recruiting Consistency Study of GlaxoSmithKline (GSK) Biologicals' MMR Vaccine (209762) (Priorix®) Comparing Immunogenicity and Safety to Merck & Co., Inc.'s MMR Vaccine (M M R®II), in Children 12 to 15 Months of Age
Conditions: Rubella;   Measles;   Mumps
Interventions: Biological: GSK Biologicals measles, mumps and rubella vaccine live (GSK 209762).;   Biological: Merck & Co., Inc.'s M-M-R®II (also called M-M-R Vax Pro®), combined measles-mumps-rubella virus vaccine.;   Biological: Varivax® (Merck & Co., Inc.);   Biological: Havrix®;   Biological: Prevnar 13® (Pfizer Inc.)
40 Not yet recruiting A Study of the Efficacy and Safety of Etrolizumab Treatment, Compared With Adalimumab and Placebo, in Inducing Disease Remission in Ulcerative Colitis Patients Who Have Not Previously Received TNF Inhibitors (Study #2)
Condition: Ulcerative Colitis
Interventions: Drug: adalimumab;   Other: adalimumab placebo;   Drug: etrolizumab;   Other: etrolizumab placebo

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Indicates status has not been verified in more than two years