247 studies found for:    stem cell transplant | Open Studies | NIH, U.S. Fed
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1 Recruiting Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants
Conditions: Stem Cell Transplantation;   Transplantation, Homologous;   Allogenic Stem Cell Transplant Recipient
Intervention:
2 Recruiting Submission of Stem Cell Transplant Data to CIBMTR and NMDP
Conditions: Autologous Stem Cell Transplantation;   Allogeneic Stem Cell Transplantation;   Solid Tumors;   Blood Cancers
Intervention:
3 Recruiting Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia
Conditions: Adult Acute Lymphoblastic Leukemia in Remission;   B-cell Adult Acute Lymphoblastic Leukemia;   L1 Adult Acute Lymphoblastic Leukemia;   L2 Adult Acute Lymphoblastic Leukemia;   Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Lymphoblastic Leukemia;   T-cell Adult Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia
Interventions: Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: dexamethasone;   Drug: dasatinib;   Drug: cytarabine;   Drug: methotrexate;   Biological: filgrastim;   Drug: methylprednisolone;   Drug: leucovorin calcium;   Drug: prednisone;   Radiation: total-body irradiation;   Drug: etoposide;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Drug: sirolimus;   Drug: tacrolimus;   Other: laboratory biomarker analysis
4 Recruiting A Phase I Trial of Safety and Immunogenicity of Gardasil(Registered Trademark) Vaccination Post Stem Cell Transplantation in Patients With and Without Immunosuppression
Conditions: Gardasil Vaccine;   Stem Cell Transplant;   Immunogenicity;   Quadrivalent HPC Vaccine;   Healthy Volunteers
Intervention: Biological: Gardasil
5 Recruiting Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer
Conditions: Renal Cell Carcinoma;   Graft-Versus-Host Disease;   Engraftment Syndrome
Interventions: Drug: Pentostatin;   Drug: Sirolimus;   Drug: Cyclophosphamide;   Procedure: Allogeneic Hematopoietic Stem Cell Transplant;   Procedure: Th2 Cell Transplantation;   Drug: Th2 Cells in Allogeneic HSCT
6 Recruiting Safety Study of Cord Blood Units for Stem Cell Transplants
Conditions: Aplastic Anemia;   Leukemia;   Myelodysplastic Syndrome (MDS);   Lymphoma
Intervention: Procedure: Cord Blood Units
7 Recruiting Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans
Conditions: Bronchiolitis Obliterans;   Constructive Bronchiolitis;   Graft Versus Host Disease
Intervention: Drug: Inhaled Cyclosporine Solution
8 Recruiting Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Conditions: Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia
Interventions: Biological: alemtuzumab;   Drug: dasatinib;   Drug: daunorubicin hydrochloride;   Drug: fludarabine phosphate;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: in vitro-treated peripheral blood stem cell transplantation;   Drug: dexamethasone;   Drug: cyclophosphamide;   Biological: filgrastim;   Biological: pegfilgrastim;   Drug: methotrexate;   Drug: leucovorin calcium;   Drug: melphalan;   Drug: tacrolimus;   Drug: etoposide phosphate;   Drug: cytarabine;   Drug: mercaptopurine;   Drug: vincristine sulfate;   Other: pharmacological study;   Other: laboratory biomarker analysis
9 Recruiting Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation
Condition: B Cell Malignancies
Intervention: Genetic: Anti-CD19-CAR-transduced T cells
10 Recruiting Montelukast to Treat Bronchiolitis Obliterans
Conditions: Bronchiolitis Obliterans;   Chronic Graft Versus Host Disease;   Leukotriene;   Montelukast;   Stem Cell Transplant
Interventions: Drug: Montelukast sodium;   Other: Flow cytometry;   Other: Laboratory biomarker analysis;   Procedure: Quality-of-life assessment
11 Recruiting Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans
Conditions: Bronchiolitis Obliterans;   Graft vs Host Disease
Intervention: Drug: Cyclosporine Inhalation Solution
12 Recruiting Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
Condition: DOCK8 Deficiency
Interventions: Drug: Fludarabine;   Procedure: Allogeneic HSC transplant;   Drug: Cyclophosphamide;   Procedure: Total Body Irradiation (TBI)
13 Recruiting Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Conditions: Severe Aplastic Anemia;   MDS (Myelodysplastic Syndrome)
Interventions: Device: Miltenyi CD34 Reagent System;   Other: Donor derived G-CSF mobilized PBC
14 Recruiting Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC
Conditions: MonoMAC;   Myelodysplastic Syndrome;   Immunodeficiency
Interventions: Procedure: Reduced-Intensity Hematopoietic Stem Cell;   Drug: Fludarabine;   Procedure: Total Body Irradiation (TBI);   Drug: Filgrastim;   Drug: Sirolimus;   Drug: Tacrolimus;   Drug: Ursodiol
15 Recruiting Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
Conditions: GATA2;   Immunodeficiency;   MDS
Interventions: Drug: Fludarabine(Fludara, Berlex Laboratories);   Drug: Busulfan (Busulfex);   Drug: Sirolimus (Rapamune);   Drug: Cyclophosphamide(CTX, Cytoxan);   Drug: Methotrexate(Methotrexate Sodium, MTX, NSC-740);   Drug: Tacrolimus (FK506, Prograf);   Procedure: Total Body Irradiation (TBI);   Drug: Equine Anti-Thymocyte Globulin
16 Recruiting Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia
Conditions: Adult Acute Megakaryoblastic Leukemia (M7);   Adult Acute Minimally Differentiated Myeloid Leukemia (M0);   Adult Acute Monoblastic Leukemia (M5a);   Adult Acute Monocytic Leukemia (M5b);   Adult Acute Myeloblastic Leukemia With Maturation (M2);   Adult Acute Myeloblastic Leukemia Without Maturation (M1);   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Adult Acute Myelomonocytic Leukemia (M4);   Adult Erythroleukemia (M6a);   Adult Pure Erythroid Leukemia (M6b);   de Novo Myelodysplastic Syndromes;   Previously Treated Myelodysplastic Syndromes;   Recurrent Adult Acute Myeloid Leukemia;   Refractory Anemia With Excess Blasts;   Secondary Myelodysplastic Syndromes;   Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: fludarabine phosphate;   Drug: busulfan;   Biological: anti-thymocyte globulin;   Procedure: allogeneic hematopoietic stem cell transplantation;   Drug: tacrolimus;   Drug: methotrexate;   Drug: azacitidine;   Other: pharmacological study;   Other: diagnostic laboratory biomarker analysis
17 Recruiting Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications
Condition: Graft-Versus-Host Disease
Intervention: Procedure: Bone Marrow Stromal Cell Infusion
18 Recruiting Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System
Conditions: Myelodysplastic Syndrome;   Hodgkin's Lymphoma;   Non-Hodgkin's Disease;   Acute Leukemia;   Multiple Myeloma
Interventions: Drug: Cyclophosphamide;   Biological: rituximab;   Drug: Methotrexate;   Drug: Sirolimus;   Drug: Cyclosporine;   Drug: Doxorubicin hydrochloride;   Drug: Etoposide;   Drug: Fludarabine phosphate;   Drug: Prednisone;   Drug: Vincristine sulfate;   Drug: Cytarabine;   Drug: Tacrolimus;   Biological: Alemtuzumab
19 Recruiting Improving Blood Stem Cell Collection and Transplant Procedures
Conditions: Myelodysplastic Syndrome (MDS);   Chronic Myelogenous Leukemia;   Acute Lymphoblastic Leukemia;   CML (Chronic Myelogenous Leukemia;   CLL (Chronic Lymphocytic Leukemia);   Acute Myeloid Leukemia (AML)
Intervention: Procedure: Stem Cell Transplantation
20 Recruiting Yttrium-90-labeled Daclizumab With Chemotherapy and Stem Cell Transplant for Hodgkin's Lymphoma
Conditions: Hodgkin Disease;   Hodgkin Lymphoma
Interventions: Drug: Filgrastim;   Drug: Plerixafor;   Drug: Yttrium-Daclizumab (CHX-A Daclizumab);   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan;   Drug: Ca(2+)-DTPA

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