332 studies found for:    sirolimus cancer | Open Studies
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Rank Status Study
21 Recruiting Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Temsirolimus plus Neratinib
22 Recruiting Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer
Conditions: Prostate Cancer;   Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: vorinostat;   Drug: temsirolimus;   Other: laboratory biomarker analysis;   Procedure: positron emission tomography/computed tomography
23 Recruiting Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone
Condition: Differentiated Thyroid Cancer
Interventions: Drug: Everolimus;   Drug: Sorafenib
24 Recruiting Carboplatin, Pegylated Liposomal Doxorubicin Hydrochloride, and Everolimus in Treating Patients With Relapsed Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
Conditions: Fallopian Tube Cancer;   Peritoneal Cavity Cancer;   Recurrent Ovarian Epithelial Cancer
Interventions: Drug: everolimus;   Drug: carboplatin;   Drug: pegylated liposomal doxorubicin hydrochloride;   Other: laboratory biomarker analysis
25 Recruiting Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Conditions: Ewing's Sarcoma;   Osteosarcoma;   Astrocytoma;   Atypical Teratoid/Rhabdoid Tumor;   Ependymoma;   Germ Cell Tumor;   Glioma;   Medulloblastoma;   Rhabdoid Tumor;   Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Rhabdomyosarcoma
Intervention: Drug: sirolimus
26 Not yet recruiting Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer;   Triple-negative Breast Cancer
Interventions: Drug: everolimus;   Drug: eribulin mesylate;   Other: pharmacological study;   Other: laboratory biomarker analysis
27 Recruiting Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer
Conditions: Ovarian Clear Cell Cystadenocarcinoma;   Stage III Ovarian Epithelial Cancer;   Stage IV Ovarian Epithelial Cancer
Interventions: Drug: paclitaxel;   Drug: carboplatin;   Drug: temsirolimus;   Drug: docetaxel;   Other: laboratory biomarker analysis
28 Recruiting Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer
Condition: Non Small Cell Lung Cancer
Interventions: Drug: Everolimus;   Drug: Pemetrexed;   Drug: Carboplatin;   Drug: Bevacizumab
29 Recruiting Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer
Condition: Advanced Cancers
Interventions: Drug: Hydroxychloroquine;   Drug: Sirolimus;   Drug: Vorinostat
30 Recruiting Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer
Conditions: Esophageal Cancer;   Neoplasms, Esophageal
Interventions: Drug: Everolimus;   Drug: Paclitaxel;   Drug: carboplatin;   Drug: cetuximab
31 Recruiting Bevacizumab, Temsirolimus, Valproic Acid, Cetuximab
Condition: Advanced Cancers
Interventions: Drug: Temsirolimus;   Drug: Bevacizumab;   Drug: Valproic Acid;   Drug: Cetuximab
32 Recruiting Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer
Condition: Rectum Cancer
Intervention: Drug: Rapamycin
33 Recruiting A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.
Condition: Breast Cancer
Interventions: Drug: Capecitabine;   Drug: Exemestane;   Drug: Everolimus
34 Recruiting Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Solid Tumors That Did Not Respond to Treatment
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Biological: panitumumab;   Drug: everolimus;   Drug: fluorouracil;   Drug: leucovorin calcium;   Drug: oxaliplatin
35 Recruiting Vandetanib With Everolimus
Condition: Advanced Cancers
Interventions: Drug: Vandetanib;   Drug: Everolimus
36 Recruiting Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Duct Cell Adenocarcinoma of the Pancreas;   Recurrent Pancreatic Cancer;   Stage IV Pancreatic Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: vismodegib;   Drug: sirolimus;   Procedure: positron emission tomography;   Procedure: computed tomography;   Other: pharmacological study;   Other: laboratory biomarker analysis;   Radiation: fludeoxyglucose F 18
37 Recruiting Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane
Conditions: Hormone Receptor Positive Malignant Neoplasm of Breast;   Metastatic Breast Cancer
Intervention: Drug: Everolimus plus Exemestane
38 Recruiting Everolimus in Refractory Testicular Germ Cell Cancer
Condition: Germ Cell Tumor
Intervention: Drug: Everolimus
39 Not yet recruiting Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Thyroid Cancer
Conditions: Recurrent Thyroid Cancer;   Stage III Follicular Thyroid Cancer;   Stage IVA Follicular Thyroid Cancer;   Stage IVB Follicular Thyroid Cancer;   Stage IVC Follicular Thyroid Cancer
Interventions: Drug: sorafenib;   Drug: everolimus
40 Recruiting Study of How Well Letrozole Works in Combination With Lapatinib Followed by an Addition of Everolimus in Postmenopausal Women With Advanced Endocrine Resistant Breast Cancer
Conditions: Breast Neoplasms;   Endocrine Breast Diseases;   Neoplasm Metastasis
Interventions: Drug: letrozole;   Drug: lapatinib;   Drug: everolimus

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