228 studies found for:    scleroderma
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Rank Status Study
21 Recruiting Gastroesophageal Reflux Treatment in Scleroderma
Conditions: Gastroesophageal Reflux Disease;   Systemic Sclerosis;   Scleroderma
Interventions: Drug: Alginic acid;   Drug: placebo (for domperidone);   Drug: Domperidone;   Drug: placebo (of alginic acid)
22 Completed A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma
Conditions: Raynaud's Phenomenon;   Digital Ulcers;   Scleroderma
Interventions: Drug: Tadalafil;   Drug: Placebo
23 Completed Psychological Treatments for Scleroderma
Conditions: Pain;   Depression;   Scleroderma;   Systemic Sclerosis
Interventions: Behavioral: Cognitive behavioral therapy;   Behavioral: Disease/health education;   Behavioral: Self-help cognitive behavioral intervention facilitated by a psychologist
24 Unknown  High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis
Condition: Scleroderma, Diffuse
Intervention: Drug: N-acetylcysteine (NAC)
25 Unknown  Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Ambrisentan with an anti-fibrotic agent to assess benefit on skin.
26 Unknown  AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
27 Completed Effectiveness and Safety of Lidocaine for Scleroderma
Condition: Scleroderma
Interventions: Drug: Lidocaine 2% without vessel constrictor;   Other: Placebo - physiological solution 0,9%
28 Recruiting Rituximab in Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Rituximab;   Drug: Placebo (NaCl)
29 Completed
Has Results
High Dose Cyclophosphamide for Treatment of Scleroderma
Condition: Scleroderma
Intervention: Drug: IV Cyclophosphamide
30 Unknown  SCOT Scleroderma Treatment Alternative Registry (STAR Registry)
Conditions: Scleroderma, Systemic;   Sclerosis
Intervention: Behavioral: Telephone Call
31 Active, not recruiting Scleroderma: Cyclophosphamide or Transplantation (SCOT)
Conditions: Scleroderma, Systemic;   Sclerosis;   Autoimmune Disease
Interventions: Procedure: Autologous stem cell transplantation;   Drug: Cyclophosphamide;   Drug: Antithymocyte globulin, equine;   Drug: Methylprednisolone;   Drug: Growth colony stimulating factor (G-CSF);   Radiation: Total body irradiation (TBI)
32 Terminated Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Conditions: Scleroderma;   Systemic Sclerosis
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Thymoglobulin;   Procedure: Leukapheresis;   Procedure: Self bone marrow transplant
33 Completed Stimulatory Autoantibodies to the Platelet-Derived Growth Factor Receptor (PDGFR) and Phosphorylation of the Platelet-Derived Growth Factor Receptor (PDGFR) in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
34 Completed Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: treprostinil diethanolamine
35 Recruiting Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem Cells
Conditions: SYSTEMIC SCLERODERMA;   ALLOGENEIC MESENCHYMAL STEM CELLS;   ADULT
Intervention: Biological: INJECTION OF ALLOGENEIC MESENCHYMAL STEM CELLS
36 Recruiting Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
Conditions: Systemic Sclerosis;   Scleroderma;   Pulmonary Hypertension;   Pulmonary Arterial Hypertension
Intervention:
37 Recruiting Scleroderma Lung: Role of Gastroesophageal Reflux, Microaspiration and Cough
Condition: Scleroderma Lung
Intervention:
38 Completed Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Scleroderma Patients
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Bosentan
39 Terminated Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma
Condition: Scleroderma
Interventions: Drug: Imatinib mesylate;   Other: Placebo
40 Terminated
Has Results
Placebo Controlled Trial of Bosentan in Scleroderma Patients
Conditions: Systemic Scleroderma;   Pulmonary Hypertension
Interventions: Drug: Bosentan;   Drug: Placebo

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Indicates status has not been verified in more than two years