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132 studies found for:    primary-progressive multiple sclerosis
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Rank Status Study
1 Recruiting Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study
Condition: Primary Progressive Multiple Sclerosis
Intervention: Other: generation of 'omic markers of disease progression
2 Recruiting Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients With Primary Progressive Multiple Sclerosis (IPPoMS)
Condition: Primary Progressive Multiple Sclerosis
Intervention: Drug: Idebenone
3 Recruiting OL, Single-arm Extension Study to the Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel-group Study Comparing the Efficacy and Safety of 0.5 mg FTY720 Administered Orally Once Daily Versus Placebo in Patients With Primary Progressive Multiple Sclerosis
Condition: Primary Progressive Multiple Sclerosis
Intervention: Drug: FTY720
4 Recruiting Idebenone for Primary Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis;   Primary Progressive Multiple Sclerosis
Intervention: Drug: Idebenone
5 Active, not recruiting FTY720 in Patients With Primary Progressive Multiple Sclerosis
Condition: Primary Progressive Multiple Sclerosis
Interventions: Drug: FTY720;   Drug: Placebo
6 Active, not recruiting Tear Analysis in the Diagnosis of Multiple Sclerosis
Condition: Primary Progressive Multiple Sclerosis
Intervention: Procedure: tears sampling
7 Not yet recruiting A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo
Condition: Primary Progressive Multiple Sclerosis
Interventions: Drug: Laquinimod;   Drug: Placebo
8 Completed A Study to Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis
Condition: Multiple Sclerosis
Interventions: Drug: placebo;   Drug: rituximab
9 Completed Natalizumab Treatment of Progressive Multiple Sclerosis
Conditions: Primary Progressive Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis
Intervention: Drug: Natalizumab
10 Active, not recruiting A Study of Ocrelizumab in Patients With Primary Progressive Multiple Sclerosis
Condition: Multiple Sclerosis, Primary Progressive
Interventions: Drug: methylprednisolone;   Drug: ocrelizumab;   Drug: Placebo
11 Recruiting A Double Blind, Randomized, Placebo Controlled, Crossover Study of the Effectiveness of Oral Fampridine in Improving Upper Limb Function in Progressive Multiple Sclerosis
Conditions: Secondary Progressive Multiple Sclerosis;   Primary Progressive Multiple Sclerosis
Interventions: Drug: Fampridine;   Drug: Placebo
12 Completed Masitinib in Patients With Primary Progressive Multiple Sclerosis (PPMS) or Relapse-free Secondary Progressive Multiple Sclerosis (SPMS)
Condition: Multiple Sclerosis
Intervention: Drug: masitinib
13 Recruiting Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition
Conditions: Relapsing-remitting Multiple Sclerosis;   Secondary-progressive Multiple Sclerosis;   Primary-progressive Multiple Sclerosis
Interventions: Drug: estriol;   Other: Placebo;   Drug: Norethindrone;   Other: Progestin Placebo
14 Terminated Hydroxyurea in Primary Progressive Multiple Sclerosis
Condition: Multiple Sclerosis
Interventions: Drug: Hydroxyurea;   Other: placebo
15 Completed Supported Treadmill Training for Progressive Multiple Sclerosis
Condition: Multiple Sclerosis
Intervention: Other: Body-weight supported treadmill training
16 Active, not recruiting Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)
Condition: Multiple Sclerosis
Interventions: Other: Progressive exercise;   Device: Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV;   Other: Modified paleolithic diet;   Dietary Supplement: Omega 3 fatty acids;   Dietary Supplement: Full Spectrum vitamin;   Dietary Supplement: Essential - hydroxytyrosol;   Dietary Supplement: Maltodextrin fiber supplement;   Dietary Supplement: Mineral boost (magnesium);   Dietary Supplement: Niacinamide;   Dietary Supplement: Methyl B12;   Dietary Supplement: Taurine;   Dietary Supplement: creatine;   Dietary Supplement: thiamine;   Dietary Supplement: riboflavin;   Dietary Supplement: N acetylcysteine;   Dietary Supplement: alpha lipoic acid;   Dietary Supplement: L acetyl carnitine;   Dietary Supplement: methyl folate;   Dietary Supplement: coenzyme Q;   Behavioral: meditation;   Behavioral: self massage;   Behavioral: learning;   Dietary Supplement: Coconut oil
17 Not yet recruiting A Phase 1 Trial of Intrathecal Rituximab for Progressive Multiple Sclerosis Patients
Conditions: Primary Progressive Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis
Intervention: Drug: Rituximab
18 Recruiting A Phase 2b/3 Study to Compare Efficacy and Safety of Masitinib to Placebo in the Treatment of Patients With Primary Progressive or Relapse-free Secondary Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis, Secondary Progressive;   Multiple Sclerosis, Primary Progressive;   Multiple Sclerosis, Relapse Free
Interventions: Drug: masitinib;   Drug: placebo
19 Completed Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis
Conditions: Secondary Progressive Multiple Sclerosis;   Primary Progressive Multiple Sclerosis
Intervention: Biological: MIS416
20 Recruiting Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS
Conditions: Primary Progressive Multiple Sclerosis;   Multiple Sclerosis, Secondary Progressive
Interventions: Drug: Andrographolides;   Drug: placebo

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