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89 studies found for:    new onset type 1 diabetes

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Rank Status Study
21 Active, not recruiting Inducing Remission in Type 1 Diabetes With Alefacept
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: alefacept;   Drug: placebo (saline)
22 Withdrawn A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52 Antibody) Therapy in Newly Diagnosed Subjects With Type 1 Diabetes Mellitus
Condition: New Onset Type 1 Diabetes Mellitus
Intervention: Drug: Campath 1H® (Alemtuzumab)
23 Unknown † Autoimmunity-Blocking Antibody for Tolerance in Recently Diagnosed Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: hOKT3gamma1 (Ala-Ala);   Other: Intensive diabetes management
24 Active, not recruiting Study of Thymoglobulin to Arrest Newly Diagnosed Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Antithymocyte globulin;   Drug: Placebo
25 Completed Effects of Rituximab on the Progression of Type 1 Diabetes in New Onset Subjects
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Anti-CD20 (rituximab)
26 Unknown † Effects of Recombinant Human Glutamic Acid Decarboxylase . . .
Condition: Type 1 Diabetes Mellitus
Interventions: Drug: GAD-Alum;   Drug: Aluminum hydroxide
27 Recruiting Safety Study to Assess Whether Proinsulin Peptide Injections Can Slow or Stop the Body Damaging Its Own Insulin-making Cells in the Pancreas in Patients Newly Diagnosed With Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Drug: Pro insulin peptide;   Drug: Saline
28 Completed Prevalence of Vitamin D Deficiency in Type 1 Diabetes Mellitus and Effect on Insulin Requirements After Supplementation With Vitamin D
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Vitamin D
29 Unknown † Autologous Dendritic Cell Therapy for Type 1 Diabetes Suppression: A Safety Study
Condition: Diabetes Mellitus, Insulin-Dependent
Interventions: Biological: Diabetes-suppressive dendritic cell vaccine;   Biological: control dendritic cells
30 Recruiting Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Conditions: Autoantibody Positive;   Non-diabetic Relatives at Risk for Type 1 Diabetes;   High Risk;   Impaired Glucose Tolerance
Intervention: Drug: Teplizumab
31 Active, not recruiting Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes
Condition: Type 1 Diabetes
Intervention: Drug: Cholecalciferol
32 Recruiting Effects Of Gamma Aminobutyric Acid On The Progression Of New Onset Juvenile Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Drug: Gamma Aminobutyric Acid (GABA);   Drug: Placebo
33 Active, not recruiting Proleukin and Rapamune in Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: IL-2;   Drug: sirolimus
34 Completed Low Dose Cyclosporin and Methotrexate Therapy in Diabetes
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: cyclosporin and methotrexate
35 Not yet recruiting The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients
Condition: Type 1 Diabetes
Interventions: Drug: Oral Cyclosporine A and Oral Lansoprazole;   Drug: Oral Placebos
36 Active, not recruiting Canakinumab Study in Individuals With Newly Diagnosed Type 1 Diabetes
Conditions: Type 1 Diabetes;   Preservation of Insulin Secretion;   Newly Diagnosed Type 1 Diabetes;   Canakinumab in Type 1 Diabetes
Intervention: Drug: canakinumab (anti IL-1beta)
37 Recruiting A Trial of High Dose Immunosuppression and Autologous Hematopoietic Stem Cell Support Versus Intensive Insulin Therapy in Adults With Early Onset Type I Diabetes Mellitus
Condition: Diabetes Mellitus, Type 1
Intervention: Biological: Autologous Hematopoietic Stem Cell Transplantation
38 Active, not recruiting Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)
Condition: Diabetes Mellitus, Insulin-Dependent
Interventions: Device: Pump therapy (CSII);   Drug: Multiple daily injections (MDI) using insulin glargine + rapid acting analog
39 Recruiting T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs
Condition: Type 1 Diabetes Mellitus
Intervention: Biological: Ex vivo Expanded Human Autologous CD4+CD127lo/-CD25+ Polyclonal Regulatory T Cells
40 Withdrawn Effect of GABA Supplementation in the Progression of Type 1 Diabetes in Children
Condition: Diabetes Mellitus
Interventions: Drug: gamma-amino-butyric acid;   Dietary Supplement: Xylitol
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† Indicates status has not been verified in more than two years