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17 studies found for:    necrotizing enterocolitis | NICHD [Lead]

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Rank Status Study
1 Recruiting Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Interventions: Procedure: Laparotomy;   Procedure: Drainage
2 Completed Observational Study of Surgical Treatment of Necrotizing Enterocolotis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Intervention:
3 Completed
Has Results 		Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
Conditions: Necrotizing Enterocolitis;   Intra-abdominal Infection
Intervention: Drug: meropenem
4 Completed Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
Conditions: Infant, Very Low Birth Weight;   Infant, Premature;   Ductus Arteriosus, Patent
Interventions: Drug: indomethacin;   Drug: Indomethacin;   Drug: Placebo
5 Completed Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies
Condition: Preterm Birth
Intervention: Drug: 17 alpha-Hydroxyprogesterone Caproate and Omega-3 fish oils
6 Completed Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: IVIG;   Drug: Placebo
7 Completed Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: Glutamine;   Drug: Placebo
8 Terminated Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)
Conditions: Bronchopulmonary Dysplasia;   Respiratory Distress Syndrome;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Minimal mechanical ventilation management;   Procedure: Routine mechanical ventilation management;   Drug: Dexamethasone;   Drug: Placebo
9 Recruiting Transfusion of Prematures Trial
Conditions: Infant, Newborn, Diseases;   Infant, Extremely Low Birth Weight;   Infant, Small for Gestational Age;   Bronchopulmonary Dysplasia (BPD);   Anemia
Interventions: Procedure: Liberal Cell Transfusion;   Procedure: Restricted red cell transfusion
10 Active, not recruiting Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity;   Continuous Positive Airway Pressure
Interventions: Procedure: Early surfactant;   Procedure: Continuous Positive Airway Pressure (CPAP);   Procedure: Target oxygen saturation of 85-89%;   Procedure: Target oxygen saturation of 91-85%
11 Completed Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
Conditions: Hyperbilirubinemia, Neonatal;   Jaundice, Neonatal;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Aggressive Phototherapy 501-750g;   Procedure: Aggressive Phototherapy 751-1000g;   Procedure: Conservative Phototherapy 501-750g;   Procedure: Conservative Phototherapy 751-1000g
12 Recruiting Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Conditions: Pregnancy;   Respiratory Distress;   Pregnancy Outcome
Intervention: Drug: Corticosteroid
13 Completed Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)
Conditions: Preterm Birth;   Pregnancy;   Multifetal
Intervention: Drug: 17 alpha-hydroxyprogesterone caproate (17P)
14 Recruiting A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)
Conditions: Congenital Cytomegalovirus Infection;   Maternal Cytomegalovirus Infection
Intervention: Drug: CMV hyperimmune globulin
15 Completed Growth Observational Study
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Intervention:
16 Completed Early Blood Pressure Management in Extremely Premature Infants
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Hypotension;   Blood Pressure
Interventions: Drug: Dopamine;   Drug: Hydrocortisone;   Drug: Infusion Placebo;   Drug: Syringe Placebo
17 Completed Inflammatory Cytokines Associated With Perinatal Brain Injury
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Cerebral Palsy
Intervention:
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† Indicates status has not been verified in more than two years