29 studies found for:    necrotizing enterocolitis | NIH
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Rank Status Study
1 Recruiting Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Interventions: Procedure: Laparotomy;   Procedure: Drainage
2 Completed Role of Epidermal Growth Factor (EGF) in Development of Necrotizing Enterocolitis
Conditions: Necrotizing Enterocolitis;   Premature Birth
Intervention:
3 Completed Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
Conditions: Necrotizing Enterocolitis;   Sepsis
Interventions: Behavioral: Fortified Pasteurized Donor Human Milk supplement;   Behavioral: Preterm Formula supplement
4 Completed Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants
Condition: Necrotizing Enterocolitis
Interventions: Procedure: laparotomy;   Procedure: primary peritoneal drainage
5 Completed Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis
Conditions: Sepsis;   Necrotizing Enterocolitis;   Meningitis;   Pneumonia
Intervention: Dietary Supplement: Vitamin A
6 Completed
Has Results
Metronidazole Pharmacokinetics (PK) in Premature Infants
Conditions: Serious Systemic Infections;   Necrotizing Enterocolitis
Intervention: Drug: Metronidazole
7 Completed Observational Study of Surgical Treatment of Necrotizing Enterocolotis
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Enterocolitis, Necrotizing;   Intestinal Perforation
Intervention:
8 Completed Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
Conditions: Infant, Very Low Birth Weight;   Infant, Premature;   Ductus Arteriosus, Patent
Interventions: Drug: indomethacin;   Drug: Indomethacin;   Drug: Placebo
9 Completed
Has Results
Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
Conditions: Necrotizing Enterocolitis;   Intra-abdominal Infection
Intervention: Drug: meropenem
10 Completed Brain Manganese Deposition in High Risk Neonates
Conditions: Necrotizing Enterocolitis;   Digestive System Abnormalities;   Cholestasis
Intervention: Dietary Supplement: remove Mn from PN if evidence of increased brain Mn on MRI
11 Completed
Has Results
PREGNANT Short Cervix Trial
Conditions: Preterm Delivery;   Short Cervix;   Short Uterine Cervical Length
Interventions: Drug: progesterone;   Drug: placebo
12 Not yet recruiting Hydrocortisone for Term Hypotension
Conditions: Infant, Newborn;   Infant, Cardiovascular Insufficiency
Interventions: Drug: Hydrocortisone;   Drug: Placebo
13 Completed Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: Glutamine;   Drug: Placebo
14 Terminated Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)
Conditions: Bronchopulmonary Dysplasia;   Respiratory Distress Syndrome;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Minimal mechanical ventilation management;   Procedure: Routine mechanical ventilation management;   Drug: Dexamethasone;   Drug: Placebo
15 Completed Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies
Condition: Preterm Birth
Intervention: Drug: 17 alpha-Hydroxyprogesterone Caproate and Omega-3 fish oils
16 Completed Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Sepsis
Interventions: Drug: IVIG;   Drug: Placebo
17 Recruiting Transfusion of Prematures Trial
Conditions: Infant, Newborn, Diseases;   Infant, Extremely Low Birth Weight;   Infant, Small for Gestational Age;   Bronchopulmonary Dysplasia (BPD);   Anemia
Interventions: Procedure: Liberal Cell Transfusion;   Procedure: Restricted red cell transfusion
18 Active, not recruiting Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity;   Continuous Positive Airway Pressure
Interventions: Procedure: Early surfactant;   Procedure: Continuous Positive Airway Pressure (CPAP);   Procedure: Target oxygen saturation of 85-89%;   Procedure: Target oxygen saturation of 91-85%
19 Completed Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
Conditions: Hyperbilirubinemia, Neonatal;   Jaundice, Neonatal;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Aggressive Phototherapy 501-750g;   Procedure: Aggressive Phototherapy 751-1000g;   Procedure: Conservative Phototherapy 501-750g;   Procedure: Conservative Phototherapy 751-1000g
20 Recruiting Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Conditions: Pregnancy;   Respiratory Distress;   Pregnancy Outcome
Intervention: Drug: Corticosteroid

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Indicates status has not been verified in more than two years