14 studies found for:    nAChR
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Rank Status Study
1 Recruiting Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
Conditions: Schizophrenia;   Impaired Cognition
Interventions: Drug: EVP-6124;   Drug: Placebo
2 Recruiting Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
Conditions: Schizophrenia;   Impaired Cognition
Interventions: Drug: EVP-6124;   Drug: Placebo
3 Recruiting A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
Conditions: Schizophrenia;   Impaired Cognition
Intervention: Drug: EVP-6124
4 Completed Nicotinic Receptor Levels After Stopping Smoking
Condition: Nicotine Addiction
Intervention: Drug: 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine
5 Recruiting PET Imaging of Extrathalamic α4β2-nicotinic Acetylcholine Receptors in Health and Disease With [18F]XTRA
Condition: Measure of Uptake of XTRA in the Brain.
Intervention: Radiation: Positron Emission Tomagraphy (PET) Imaging
6 Recruiting Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease
Conditions: Alzheimer's Disease;   Dementia
Interventions: Drug: Drug: EVP-6124;   Drug: Placebo
7 Recruiting Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease
Conditions: Alzheimer's Disease;   Dementia
Interventions: Drug: Drug: EVP-6124;   Drug: Placebo
8 Not yet recruiting Study of the Safety and Clinical Effects of 2 Doses of EVP-6124 in Subjects With Alzheimer's Disease Who Complete Study EVP-6124-024 or EVP-6124-025
Conditions: Alzheimer's Disease;   Dementia
Intervention: Drug: EVP-6124
9 Recruiting Brain Nicotine Receptor Density in Veteran Smokers
Condition: Positron Emission Tomography
Intervention:
10 Suspended Study of Nicotine Patches in Patients With Sarcoidosis
Condition: Pulmonary Sarcoidosis
Intervention: Drug: nicotine patch
11 Completed Brain Imaging in Alzheimer's Disease
Condition: Alzheimer Disease
Intervention: Drug: [123] 5-I-A-85380
12 Recruiting Role of SLURP-1 in Melanoma and Melanoma Stem Cells
Condition: Melanoma;
Intervention:
13 Completed Anti-inflammatory Effects of GTS-21 After LPS
Conditions: Endotoxemia;   Sepsis;   Vagal Activity
Interventions: Drug: GTS-21, [3-(2,4-dimethoxybenzylidene)-anabaseine dihydrochloride];   Drug: Placebo;   Drug: Lipopolysaccharide E. Coli 113:H 10:K negative
14 Active, not recruiting Nicotine Receptor Levels and Smoking Cessation
Conditions: Smoking Cessation;   Nicotine Addiction
Intervention: Drug: Nictonie Patch, Verenacline

Indicates status has not been verified in more than two years