54 studies found for:    mk-0653c
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Rank Status Study
1 Completed
Has Results
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)
Condition: Hypercholesterolemia
Interventions: Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Ezetimibe/atorvastatin;   Drug: Placebo to atorvastatin;   Drug: Placebo to ezetimibe;   Drug: Placebo to ezetimibe/atorvastatin
2 Completed
Has Results
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)
Condition: Hypercholesterolemia
Interventions: Drug: Atorvastatin;   Drug: Ezetimibe;   Drug: Ezetimibe/atorvastatin;   Drug: Placebo to atorvastatin;   Drug: Placebo to ezetimibe;   Drug: Placebo to ezetimibe/atorvastatin
3 Completed
Has Results
MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe 10 mg;   Drug: atorvastatin;   Drug: Comparator: rosuvastatin
4 Completed Eze/Simva Switch Study in Diabetics
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: MK0653A, ezetimibe (+) simvastatin / Duration of Treatment: 6 Weeks;   Drug: Comparator: atorvastatin / Duration of Treatment: 6 Weeks
5 Completed
Has Results
Effect of Ezetimibe Treatment on Low-density Lipoprotein Cholesterol (LDL-C) Levels in Participants With Coronary Heart Disease (CHD) Already Treated With a Statin (MK-0653A-205 AM1)
Condition: Hypercholesterolemia
Intervention: Drug: Ezetimibe
6 Completed
Has Results
Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)
Condition: Primary Hypercholesterolemia
Interventions: Drug: ezetimibe;   Drug: Placebo
7 Completed
Has Results
Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe/simvastatin 10/40;   Drug: atorvastatin 40 mg;   Drug: atorvastatin 20 mg
8 Completed
Has Results
A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe (+) simvastatin;   Drug: Comparator: atorvastatin;   Drug: Comparator: rosuvastatin
9 Completed
Has Results
Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: simvastatin (+) ezetimibe;   Drug: Comparator: atorvastatin
10 Completed
Has Results
Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)
Conditions: Cardiovascular Disorder;   Diabetes Mellitus
Interventions: Drug: ezetimibe (+) simvastatin;   Drug: simvastatin 40 mg or atorvastatin 20 mg;   Drug: Rosuvastatin;   Drug: atorvastatin 10 mg or simvastatin 20 mg
11 Completed A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease
Condition: Coronary Disease
Interventions: Drug: MK0653, ezetimibe / Duration of Treatment: 27 Weeks;   Drug: MK0733, simvastatin / Duration of Treatment: 27 Weeks;   Drug: Comparator: simvastatin / Duration of Treatment: 27 Weeks
12 Completed A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: MK0653A, ezetimibe (+) simvastatin;   Drug: Comparators: simvastatin and ezetimibe
13 Completed
Has Results
A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)
Conditions: Dyslipidemia;   Hypercholesterolemia
Intervention: Other: Test Meal
14 Completed A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)
Conditions: Type 2 Diabetes Mellitus;   Hypercholesterolemia
Interventions: Drug: MK0653A, ezetimibe (+) simvastatin;   Drug: Duration of Treatment: 4 wk placebo run in then 6 wk active;   Drug: Comparator: atorvastatin
15 Completed
Has Results
A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe (+) simvastatin;   Drug: Comparator : rosuvastatin calcium;   Drug: Comparator: Placebo (unspecified)
16 Completed
Has Results
A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea
Condition: Hypercholesterolemia
Interventions: Drug: simvastatin (+) ezetimibe;   Drug: Comparator: atorvastatin
17 Completed
Has Results
Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe (+) simvastatin;   Drug: atorvastatin
18 Withdrawn A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406)
Condition: Dyslipidemia
Interventions: Drug: Ezetimibe/simvastatin;   Drug: Other Statin
19 Completed Observational Study to Evaluate LDL-C Lowering Effect of Ezetimibe (0653-070)
Condition: Hypercholesterolemia
Intervention: Drug: MK0653, ezetimibe / Duration of Treatment: 4 Weeks
20 Completed MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: MK0653A, ezetimibe (+) simvastatin;   Drug: Comparator: atorvastatin

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Indicates status has not been verified in more than two years