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44 studies found for:    metabolic syndrome | Open Studies | Interventional Studies | Adult | Phase 1, 2, 3 | Industry

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Rank Status Study
1 Recruiting Effects of Pitavastatin on Monocyte, Endothelial Dysfunction and HDL-C in Subjects With Metabolic Syndrome
Condition: Metabolic Syndrome
Intervention: Drug: Pitavastatin
2 Recruiting Study of Sildenafil Citrate on Insulin Resistance in African American
Conditions: Metabolic Syndrome;   Obesity
Intervention: Drug: Sildenafil, placebo
3 Recruiting Prediction of Severity of Liver Disease by a 13C Octanoate Breath Test (OBT)
Conditions: Metabolic Syndrome;   Nonalcoholic Fatty Liver Disease
Intervention: Drug: Sodium Octanoate
4 Unknown † Efficacy of Laflavon in Lowering Triglycerides and Raising High-Density Lipoprotein (HDL)
Condition: Metabolic Disease
Intervention: Dietary Supplement: LaFlavon
5 Recruiting Impact of Roflumilast on Visceral Adiposity and Metabolic Profile in Chronic Obstructive Pulmonary Disease
Conditions: Chronic Obstructive Pulmonary Disease;   Metabolic Syndrome
Interventions: Drug: Roflumilast;   Drug: Placebo
6 Recruiting Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Conditions: Gestational Diabetes Mellitus;   Type 2 Diabetes Mellitus;   Metabolic Syndrome;   Impaired Glucose Tolerance;   Impaired Fasting Glucose
Interventions: Drug: Metformin XR only;   Drug: Metformin XR plus liraglutide
7 Recruiting Phase IIb Study to Evaluate the Efficacy and Safety of GFT505 Versus Placebo in Patients With Non-Alcoholic Steatohepatitis (NASH)
Condition: Non-Alcoholic Steatohepatitis (NASH)
Interventions: Drug: GFT505 80mg;   Drug: GFT505 120mg;   Drug: Placebo
8 Recruiting The Cardiac Benefit of Testosterone Replacement in Men With Low Testosterone Levels With Coronary Artery Disease After Successful Intervention of the Blockage or Narrowed Heart Artery
Condition: Coronary Artery Disease
Interventions: Drug: AndroGel 5 Grams;   Drug: Placebo
9 Recruiting Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé)
Conditions: HIV;   HIV Infections
Interventions: Drug: emtricitabine/tenofovir + lopinavir/ritonavir (WHO recommended second line);   Drug: abacavir + didanosine + lopinavir/ritonavir (WHO recommended second line);   Drug: emtricitabine/tenofovir + darunavir + ritonavir (Second line strategy under evaluation)
10 Recruiting Investigator Initiated Study of the Effects of Androgen Therapy on Carbohydrate and Lipid Metabolism In Elderly Men
Conditions: Aging;   Obesity;   Insulin Resistance;   Hypogonadism
Intervention: Drug: Topical testosterone (Androgel) 10 g/day
11 Not yet recruiting Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin
Conditions: Polycystic Ovary Syndrome;   Insulin Resistance
Interventions: Drug: Metformin;   Drug: Clomiphene citrate
12 Recruiting Treosulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Condition: Nonmalignant Neoplasm
Interventions: Procedure: umbilical cord blood transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: allogeneic bone marrow transplantation;   Drug: fludarabine phosphate;   Drug: treosulfan;   Radiation: total-body irradiation;   Drug: tacrolimus;   Drug: methotrexate;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Genetic: DNA analysis;   Other: laboratory biomarker analysis;   Genetic: cytogenetic analysis;   Biological: anti-thymocyte globulin
13 Recruiting Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)
Condition: Polycystic Ovary Syndrome (PCOS)
Interventions: Drug: DLBS3233;   Drug: Metformin XR;   Drug: Placebo caplet of Metformin XR;   Drug: Placebo capsule of DLBS3233
14 Recruiting Study of Bacteria on Mood and Bowel Symptoms in Patients With Irritable Bowel Syndrome
Conditions: Irritable Bowel Syndrome;   IBS
Interventions: Dietary Supplement: Bifidobacterium longum;   Other: Maltodextrin
15 Recruiting Therapeutic Approaches to HAART-Induced Lipodystrophy
Conditions: HIV Infections;   Lipodystrophy
Intervention: Drug: Metreleptin (Leptin)
16 Recruiting Myelodysplastic Syndromes (MDS) Event Free Survival With Iron Chelation Therapy Study
Condition: Myelodysplastic Syndromes
Interventions: Drug: Deferasirox;   Drug: Deferasirox placebo
17 Not yet recruiting An Open-Label Phase 1/2 Study to Assess the Safety, Efficacy and Dose of Study Drug UX003 Recombinant Human Beta-glucuronidase (rhGUS) Enzyme Replacement Therapy in Patients With MPS 7
Condition: Mucopolysaccharidosis Type 7
Intervention: Drug: UX003
18 Recruiting Safety Study of HepaStem for the Treatment of Urea Cycle Disorders (UCD) and Crigler-Najjar Syndrome (CN)
Conditions: Urea Cycle Disorders,;   Crigler Najjar Syndrome
Intervention: Biological: HepaStem
19 Recruiting A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome
Condition: Familial Chylomicronemia Syndrome (FCS)
Interventions: Drug: LCQ908;   Drug: Placebo
20 Recruiting Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.
Condition: Familial Chylomicronemia Syndrome (FCS) (HLP Type I)
Intervention: Drug: LCQ908
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† Indicates status has not been verified in more than two years