40 studies found for:    mdv3100 | Open Studies
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Rank Status Study
1 Recruiting Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer
Condition: Breast Cancer
Intervention: Drug: enzalutamide
2 Recruiting Safety Study of Enzalutamide in Combination With Exemestane in Patients With Advanced Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Enzalutamide;   Drug: exemestane;   Drug: Placebo (for enzalutamide)
3 Recruiting Enzalutamide in Patients With High-risk Prostate Cancer
Condition: Adenocarcinoma of the Prostate
Intervention: Drug: enzalutamide
4 Recruiting Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer
Conditions: Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: mifepristone;   Other: laboratory biomarker analysis;   Other: pharmacological study
5 Recruiting Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients
Condition: Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Abiraterone;   Drug: Placebo for Enzalutamide;   Drug: Prednisone
6 Not yet recruiting A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Conditions: Prostate Cancer;   Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
7 Not yet recruiting LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: bicalutamide;   Procedure: orchiectomy;   Drug: leuprolide acetate;   Drug: goserelin acetate;   Other: laboratory biomarker analysis
8 Recruiting RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistant (The RESTORE Study)
Condition: Prostate Cancer
Interventions: Drug: Testosterone cypionate;   Drug: Testosterone Enanthate;   Drug: Abiraterone acetate;   Drug: Enzalutamide
9 Recruiting Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Condition: Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: Enzalutamide;   Drug: LHRHa
10 Not yet recruiting Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer and Previous Treatment With Docetaxel
Condition: Prostate Cancer, Castrate-resistant
Interventions: Drug: Everolimus;   Drug: Enzalutamide
11 Recruiting Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Other: laboratory biomarker analysis
12 Recruiting Enzalutamide + External Beam Rt For Prostate
Condition: Intermediate Risk Prostate Cancer
Interventions: Drug: Enzalutamide;   Radiation: External Beam Radiation
13 Recruiting Enzalutamide in Combination With Gemcitabine and Nab-Paclitaxel for the Treatment of Advanced Pancreatic Cancer
Condition: Pancreatic Cancer
Interventions: Drug: Enzalutamide;   Drug: Gemcitabine;   Drug: Nab-paclitaxel
14 Recruiting Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer
Condition: Nonmetastatic Castration-Resistant Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Placebo
15 Recruiting Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer With Correlative Assessment of Androgen Receptor Signaling
Condition: Prostate Cancer
Intervention: Drug: Enzalutamide
16 Recruiting Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)
Condition: Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: Androgen Deprivation;   Radiation: Radiation Therapy
17 Recruiting A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
18 Recruiting A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide
Condition: Metastatic Castration- Resistant Prostate Cancer (mCRCP)
Intervention: Drug: Enzalutamide
19 Recruiting Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Recurrent Prostate Cancer;   Stage IIB Prostate Cancer;   Stage III Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Goserelin acetate;   Drug: Leuprolide acetate;   Radiation: Radiation therapy
20 Recruiting A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Subjects With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) and Estrogen Receptor Negative (ER-) Metastatic or Locally Advanced Breast Cancer
Conditions: Advanced Breast Cancer;   Human Epidermal Growth Factor Receptor 2 (HER2);   HER2 Amplified
Interventions: Drug: enzalutamide;   Drug: trastuzumab

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Indicates status has not been verified in more than two years