50 studies found for:    mdv3100 | Open Studies
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1 Recruiting Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer
Condition: Breast Cancer
Interventions: Drug: enzalutamide;   Drug: anastrozole;   Drug: exemestane;   Drug: fulvestrant
2 Recruiting Safety Study of Enzalutamide in Combination With Exemestane in Patients With Advanced Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Enzalutamide;   Drug: exemestane;   Drug: Placebo (for enzalutamide)
3 Recruiting Enzalutamide in Patients With High-risk Prostate Cancer
Condition: Adenocarcinoma of the Prostate
Intervention: Drug: enzalutamide
4 Recruiting Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate Cancer
Conditions: Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: mifepristone;   Other: laboratory biomarker analysis;   Other: pharmacological study
5 Not yet recruiting A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Conditions: Prostate Cancer;   Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
6 Recruiting Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer
Condition: Prostate Cancer, Castrate-resistant
Interventions: Drug: Everolimus;   Drug: Enzalutamide
7 Recruiting RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistant (The RESTORE Study)
Condition: Prostate Cancer
Interventions: Drug: Testosterone cypionate;   Drug: Testosterone Enanthate;   Drug: Abiraterone acetate;   Drug: Enzalutamide
8 Recruiting Molecular Features and Pathways in Predicting Resistance in Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Enzalutamide
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Other: laboratory biomarker analysis;   Other: cytology specimen collection procedure
9 Recruiting Salvage Therapeutic Radiation With Enzalutamide and ADT in Men With Recurrent Prostate Cancer (STREAM)
Condition: Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: Androgen Deprivation;   Radiation: Radiation Therapy
10 Recruiting Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Condition: Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: Enzalutamide;   Drug: LHRHa
11 Recruiting Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer
Conditions: Nonmetastatic Castration-Resistant Prostate Cancer;   Prostate Cancer;   Cancer of the Prostate
Interventions: Drug: Enzalutamide;   Drug: Placebo
12 Recruiting Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Other: laboratory biomarker analysis
13 Recruiting A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Condition: Metastatic Castration-Resistant Prostate Cancer
Intervention: Drug: Enzalutamide
14 Recruiting Enzalutamide + External Beam Rt For Prostate
Condition: Intermediate Risk Prostate Cancer
Interventions: Drug: Enzalutamide;   Radiation: External Beam Radiation
15 Recruiting A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide
Condition: Metastatic Castration- Resistant Prostate Cancer (mCRPC)
Intervention: Drug: Enzalutamide
16 Not yet recruiting Crizotinib in Combination With Enzalutamide in Metastatic Castration-resistant Prostate Cancer
Condition: Castration-resistant Prostate Cancer
Interventions: Drug: Crizotinib;   Drug: Enzalutamide
17 Recruiting A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Subjects With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) and Estrogen Receptor Negative (ER-) Metastatic or Locally Advanced Breast Cancer
Conditions: Advanced Breast Cancer;   Human Epidermal Growth Factor Receptor 2 (HER2);   HER2 Amplified
Interventions: Drug: enzalutamide;   Drug: trastuzumab
18 Recruiting LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: enzalutamide;   Drug: bicalutamide;   Procedure: orchiectomy;   Drug: leuprolide acetate;   Drug: goserelin acetate;   Other: laboratory biomarker analysis
19 Recruiting Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: Enzalutamide;   Drug: Leuprolide acetate;   Radiation: radiation
20 Recruiting Phase II Trial of Enzalutamide for Castrate-resistant Prostate Cancer With Correlative Assessment of Androgen Receptor Signaling
Condition: Prostate Cancer
Intervention: Drug: Enzalutamide

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Indicates status has not been verified in more than two years