89 studies found for:    kuvan
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Rank Status Study
21 Recruiting Kuvan in People With Schizophrenia and Schizoaffective Disorder
Conditions: Schizophrenia;   Schizoaffective Disorder
Interventions: Drug: Kuvan;   Drug: Multivitamin
22 Terminated Behavioral Effects of Kuvan in Children With Mild Phenylketonuria
Condition: Phenylketonuria
Intervention: Drug: Kuvan
23 Completed
Has Results
Nutritional and Neurotransmitter Changes in PKU Subjects on BH4
Condition: Phenylketonuria
Intervention: Drug: KuvanTM Therapy
24 Completed
Has Results
Tetrahydrobiopterin Treatment in Children With Idiopathic Cognitive Developmental Disorders
Condition: Autism Spectrum Disorder
Intervention: Drug: sapropterin dihydrochloride
25 Completed Effects of Tetrahydrobiopterin on Blood Pressure
Condition: Hypertension
Intervention: Drug: Tetrahydrobiopterin
26 Withdrawn Trial of Kuvan in Lesch-Nyhan Disease
Condition: Behavioral Manifestations of Lesch-Nyhan Disease
Intervention: Drug: sapropterin
27 Completed A Study of the Effects of 6R-BH4 on Blood Pressure in Subjects With Poorly Controlled Systemic Hypertension
Condition: Hypertension
Intervention: Drug: 6R-BH4 (sapropterin dihydrochloride)
28 Enrolling by invitation Bone Mineral Density in Adults With Hyperphenylalaninemia on Kuvan Therapy
Conditions: Hyperphenylalaninemia;   Phenylketonuria
Intervention: Drug: Sapropterin
29 Terminated Neuroimaging and Neurocognitive Assessment and Response to Sapropterin Dihydrochloride Treatment in Phenylketonuria
Condition: PKU
Interventions: Dietary Supplement: diet;   Drug: sapropterin dihydrochloride
30 Recruiting Sapropterin on Cognitive Abilities in Young Adults With Phenylketonuria
Condition: Phenylketonuria
Interventions: Drug: Sapropterin;   Drug: Placebo
31 Terminated Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety
Condition: Phenylalanine Hydroxylase Deficiencies
Intervention: Drug: tetrahydrobiopterin (BH4)
32 Completed
Has Results
Sapropterin as a Treatment for Autistic Disorder
Condition: Autistic Disorder
Interventions: Drug: sapropterin;   Drug: Placebo
33 Unknown  Response to Phenylketonuria to Tetrahydrobiopterin (BH4)
Condition: Phenylketonuria
Intervention: Drug: tetrahydrobiopterin (BH4)
34 Unknown  Effect of 6R-BH4 Treatment in Coronary Artery Disease (OXBIO Study)
Condition: Coronary Artery Disease
Intervention: Drug: 6R-BH4
35 Unknown  The Purpose of This Pilot Study is to Assess the Impact of KUVAN® (Sapropterin Dihydrochloride) on Gastric Relaxation in Women With Diabetic Gastroparesis.
Condition: Gastroparesis
Intervention: Drug: sapropterin dihydrochloride
36 Recruiting Endothelial Facilitation in Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Simvastatin + L-Arginine + Tetrahydrobiopterin
37 Recruiting Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
Conditions: Menopause;   Aging;   Vascular Health
Interventions: Drug: KUVAN;   Drug: Placebo;   Drug: Cetrotide;   Drug: Climara;   Drug: Placebo transdermal patch
38 Completed Study of BH4, a New and Simple Treatment of Mild PKU
Condition: Phenylketonuria
Intervention: Drug: 5,6,7,8-tetrahydrobiopterin
39 Completed 6R-BH4 Pulmonary Arterial Hypertension Study
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: sapropterin dihydrochloride (6R-BH4)
40 Active, not recruiting Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria
Conditions: Kidney Disease;   Albuminuria
Interventions: Drug: Tetrahydrobiopterin (6R BH4);   Dietary Supplement: Vitamin C

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Indicates status has not been verified in more than two years