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21 studies found for:    immune tolerance niaid | Open Studies
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Rank Status Study
1 Recruiting Defining Immune Tolerance in ANCA-associated Vasculitis (AAV)
Condition: ANCA-associated Vasculitis
Intervention:
2 Recruiting Bone Marrow Transplantation and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance
Condition: Kidney Transplantation
Interventions: Biological: Antithymocyte globulin (ATG);   Drug: Fludarabine;   Drug: Low dose Pre-transplant cyclophosphamide;   Radiation: Total Body Irradiation;   Drug: Acetaminophen;   Drug: Diphenhydramine;   Drug: Methylprednisolone;   Biological: Bone Marrow;   Drug: MESNA;   Drug: Mycophenolate mofetil (MMF);   Drug: Prednisone;   Drug: Filgrastim;   Drug: High dose post-transplant cyclophosphamide
3 Not yet recruiting Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy
Condition: Cat Allergy
Interventions: Biological: AMG 157;   Biological: Cat Immunotherapy;   Biological: Placebo for Cat Immunotherapy;   Biological: Placebo for AMG 157
4 Recruiting CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1
Conditions: Abnormal Glucose Tolerance;   Type 1 Diabetes
Interventions: Drug: CTLA4-Ig (Abatacept);   Drug: Placebo
5 Recruiting Evaluating the Safety, Tolerance, Drug Interactions, and Effective Dosing of a Raltegravir-Containing Antiretroviral Therapy (ART) Regimen in ART-Naive Children Infected With HIV and TB
Conditions: HIV Infections;   Tuberculosis
Intervention: Drug: Raltegravir
6 Recruiting Peanut Oral Immunotherapy in Children
Condition: Peanut Hypersensitivity
Interventions: Biological: Peanut Oral Immunotherapy - Liquid Extract;   Biological: Placebo for Peanut Oral Immunotherapy - Liquid Extract form;   Biological: Peanut Oral Immunotherapy - Peanut Flour;   Biological: Placebo for Peanut Oral Immunotherapy - Peanut Flour
7 Recruiting Assessment of Alterations in Immune Function During Pregnancy and Post Parturition
Conditions: Pregnancy;   Immune Function
Intervention:
8 Recruiting Tolerance Following Peanut Oral Immunotherapy
Condition: Peanut Allergy
Interventions: Drug: Peanut Flour;   Drug: Oat Flour
9 Recruiting Delayed Tolerance in Recipients of Living Kidney Allografts by Donor FCRx Infusion
Condition: Kidney Transplantation
Intervention: Biological: Hematopoietic Stem Cell Transplant/novel platform technology
10 Not yet recruiting TCZ in New-onset Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Interventions: Drug: Tocilizumab;   Drug: Placebo for Tocilizumab
11 Not yet recruiting Rituximab and Belimumab for Lupus Nephritis
Condition: Lupus Nephritis
Interventions: Biological: Rituximab;   Drug: Cyclophosphamide;   Drug: Prednisone;   Drug: Methylprednisolone;   Drug: Diphenhydramine;   Drug: Acetaminophen;   Biological: Belimumab
12 Recruiting Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral Therapy
Conditions: Liver Disease;   Steatohepatitis;   HIV
Intervention:
13 Recruiting Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Conditions: Autoantibody Positive;   Non-diabetic Relatives at Risk for Type 1 Diabetes;   High Risk;   Impaired Glucose Tolerance
Intervention: Drug: Teplizumab
14 Recruiting Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Oral Insulin
15 Not yet recruiting Pilot Study of Bydureon to Treat Diabetes in HIV-infected Adults
Conditions: Human Immunodeficiency Virus Infection;   Diabetes Mellitus
Intervention: Drug: extended-release exenatide
16 Not yet recruiting ATG-GCSF in New Onset Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Drug: Anti-Thymocyte Globulin (ATG)/Placebo;   Drug: Granulocyte colony stimulating factor (GCSF)
17 Recruiting Safety and Immunogenicity of Two Live, Attenuated Oral Shigella Sonnei Vaccines: WRSs2 and WRSs3
Condition: Shigella Infection
Interventions: Biological: WRSs3;   Other: Placebo;   Biological: WRSs2
18 Not yet recruiting Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole
Condition: Neurocysticercosis
Interventions: Drug: Oxfendazole;   Drug: Placebo
19 Recruiting Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris
Condition: Psoriasis
Interventions: Biological: Ustekinumab;   Biological: Abatacept;   Drug: Placebo for Ustekinumab;   Drug: Placebo for Abatecept
20 Not yet recruiting Cat Pilot Study - Environmental Exposure Chamber (EEC) vs. Nasal Allergen Challenge (NAC)
Condition: Hypersensitivity, Immediate
Interventions: Procedure: Nasal Allergen Challenge;   Other: Environmental Exposure Chamber;   Biological: Cat allergen (FelD1)

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