213 studies found for:    heart surgery OR coronary artery bypass surgery OR heart transplant | Open Studies | NIH, U.S. Fed
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Rank Status Study
21 Recruiting Lidocaine For Neuroprotection During Cardiac Surgery
Condition: Cognitive Decline
Interventions: Drug: Lidocaine;   Drug: Placebo
22 Recruiting A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics
Conditions: Transposition of the Great Arteries;   Tetralogy of Fallot;   Ventricular Septal Defect
Intervention: Drug: Dexmedetomidine
23 Recruiting Building Research Initiative Group: Chronic Illness Management and Adherence in Transplantation
Condition: Heart Transplant
Intervention:
24 Recruiting International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
Conditions: Cardiovascular Diseases;   Coronary Disease;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia
Interventions: Procedure: cardiac catheterization;   Procedure: coronary artery bypass graft surgery;   Procedure: percutaneous coronary intervention;   Behavioral: Lifestyle;   Drug: Medication
25 Recruiting Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Condition: Congestive Heart Failure
Intervention:
26 Recruiting Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Conditions: Congenital Heart Disease;   Disorder of Fetus or Newborn
Interventions: Drug: Methylprednisolone;   Drug: Placebo
27 Recruiting Cardiac Surgery Neuroprotection Study in Elders
Conditions: Post-operative Cognitive Decline;   Post-operative Delirium
Interventions: Drug: Aspart insulin;   Drug: Placebo
28 Recruiting Red Cell Storage Duration Study
Conditions: Cardiac Surgery;   Erythrocyte Transfusion
Interventions: Biological: Red blood cell units stored <= 10 days;   Biological: Red blood cell units stored >= 21 days
29 Recruiting Impact of Blood Storage Duration on Physiologic Measures
Conditions: Cardiac Surgery;   Erythrocyte Transfusion
Intervention:
30 Recruiting Randomized Endo-Vein Graft Prospective
Condition: Coronary Artery Bypass Grafting
Intervention: Procedure: Vein Harvesting Procedures
31 Recruiting Microparticles in Stored RBC as Potential Mediators of Transfusion Complications
Condition: Coronary Artery Bypass Graft Surgery
Interventions: Biological: Washed RBC;   Biological: Unwashed RBC
32 Recruiting TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
Condition: Cardiovascular Diseases
Intervention:
33 Recruiting MR, Histologic And EM Imaging Of Intravenous Ferumoxytol In Central Nervous System (CNS) Inflammation
Conditions: Nervous System Diseases;   Diagnostic Imaging
Intervention: Drug: Ferumoxytol
34 Recruiting Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory Support
Conditions: Advanced Heart Failure;   Systolic Heart Failure
Intervention: Other: No Intervention
35 Unknown  Reducing Risk in Cardiac Rehabilitation: Partners Together in Health (PaTH) Intervention Study
Conditions: Coronary Heart Disease;   Cardiac Rehabilitation
Intervention: Behavioral: Partners Together in Health (PaTH) Intervention
36 Recruiting HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy
Condition: Hypertrophic Cardiomyopathy
Intervention: Other: None - this is an observational study
37 Recruiting Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty
Condition: Saphenous Vein Graft Atherosclerosis
Interventions: Device: Bare Metal Stent;   Device: Drug-Eluting Stent;   Drug: Blinded clopidogrel;   Drug: Placebo;   Drug: Thienopyridine (open-label)
38 Recruiting Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Conditions: Emphysema;   Chronic Obstructive Pulmonary Disease (COPD);   Cystic Fibrosis;   Pulmonary Fibrosis;   Bronchiectasis;   Sarcoidosis;   Pulmonary Hypertension;   Alpha-1 Antitrypsin Deficiency
Interventions: Procedure: Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™;   Device: STEEN Solution™
39 Recruiting The Evaluation of VAD InterVEntion Before Inotropic Therapy
Condition: Congestive Heart Failure
Interventions: Device: HM II® (HeartMate II® LVAD);   Other: OMM (Optimal Medical Management)
40 Recruiting Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve
Conditions: Postoperative Delirium;   PD;   Postoperative Cognitive Dysfunction;   POCD
Interventions: Drug: Precedex (Dexmedetomidine);   Drug: Placebo

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