59 studies found for:    gene expression | Open Studies | Interventional Studies | breast cancer | Phase 2, 3
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Rank Status Study
1 Recruiting Correlate BRCA1 Protein Expression With Response to DNA Damaging Chemotherapy
Condition: Breast Cancer
Intervention: Drug: Pegylated liposomal doxorubicin
2 Recruiting A Study to Evaluate Denosumab in Young Patients With Primary Breast Cancer
Condition: Breast Neoplasms
Intervention: Drug: Denosumab
3 Recruiting A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)
Conditions: Pre-treated Postmenopausal Patients With ER/PgR-negative/AR-positive or ER;   and/or PgR-positive/AR-positive Metastatic Breast Cancer
Intervention: Drug: DHEA (Dehydroepiandrosterone)
4 Recruiting Evaluate Trastuzumab Plus Standard Chemotherapy Given Before Surgery in Breast Cancer Patients With Low HER 2 Expression
Condition: Breast Cancer
Interventions: Drug: nab-paclitaxel;   Drug: trastuzumab;   Drug: Doxorubicin;   Drug: cyclophosphamide
5 Recruiting PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Lapatinib;   Drug: Trastuzumab;   Drug: Endocrine Therapy;   Drug: Paclitaxel
6 Recruiting CR1447 in Endocrine Responsive-HER2neg and TN-ARpos Breast Cancer
Conditions: Metastatic Breast Adenocarcinoma;   Breast Cancer
Intervention: Drug: CR1447
7 Recruiting A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With LCL161 in Patients With Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Paclitaxel + LCL161;   Drug: paclitaxel
8 Recruiting DIG-HIF1 Pharmacodynamic Trial in Newly Diagnosed Operable Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Digoxin
9 Not yet recruiting Correlation of Genomic Variation in Enzymes Responsible for Metabolism of Capecitabine With Drug Metabolism
Condition: Breast Cancer
Intervention: Drug: Capecitabine
10 Recruiting PET Study of Breast Cancer Patients Using [68Ga]ABY-025
Condition: Breast Cancer
Intervention: Drug: [68Ga]ABY-025
11 Recruiting Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors
Condition: Breast Cancer
Interventions: Drug: Tamoxifen Citrate;   Drug: Placebo;   Procedure: Digital mammography;   Other: immunohistochemistry staining method;   Other: pharmacological study;   Other: laboratory biomarker analysis;   Genetic: protein expression analysis;   Procedure: fine-needle aspiration;   Other: pharmacogenomic studies;   Other: questionnaire administration
12 Recruiting Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer
Condition: Operable Breast Cancer
Intervention: Drug: 0.5% lignocaine 60mM
13 Not yet recruiting AR and ER Imaging in Metastatic Breast Cancer
Condition: Metastatic Breast Cancer
Interventions: Other: FDHT-PET scan;   Other: FES-PET scan;   Other: CT-scan;   Other: Bone scintigraphy;   Other: Tumor biopsy
14 Recruiting Safety and Efficacy of BKM120 and Lapatinib in HER2+/PI3K-activated, Trastuzumab-resistant Advanced Breast Cancer
Condition: Breast Cancer
Intervention: Drug: BKM120 + lapatinib
15 Recruiting Pharmacogenomic Study of Neoadjuvant Eribulin for HER2 Non-overexpressing Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Eribulin
16 Not yet recruiting The Safety and Effects of Gefitinib in Triple-negative,EGFR Positive Metastatic Breast Cancer
Condition: Breast Cancer
Intervention: Drug: gefitinib
17 Recruiting A Study of Pegylated Liposomal Doxorubicin and Cyclophosphamide in Her2-negative Stage I and II Breast Cancer Patients
Condition: Breast Cancer
Interventions: Drug: Epirubicin+Cyclophosphamide;   Drug: liposomal-doxorubicin+Cyclophosphamide
18 Not yet recruiting Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer
Conditions: Breast Cancer;   Breast Carcinoma;   Breast Tumors;   Malignant Neoplasm of Breast
Interventions: Drug: Paclitaxel;   Drug: Alisertib
19 Recruiting Clinical Value of 89Zr-trastuzumab PET
Condition: Metastatic Breast Cancer
Intervention: Drug: 89Zr-trastuzumab injection
20 Recruiting Re-expression of ER in Triple Negative Breast Cancers
Conditions: Breast Cancer;   Breast Tumors;   Breast Neoplasms
Intervention: Drug: Decitabine, LHB589, Tamoxifen

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