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48 studies found for:    exendin

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Rank Status Study
1 Completed Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans
Condition: Hyperglycemia
Interventions: Drug: GLP-1 control;   Drug: GLP-1 and Exendin(9-39) 300;   Drug: saline control;   Drug: GLP-1 and Exendin(9-39) 600;   Drug: GLP-1 and Exendin(9-39) 900;   Drug: GLP-1 and Exendin(9-39) 1200
2 Completed Effects of Exendin(9-39) on Gastroduodenal Motility
Conditions: Digestive Physiology;   Gastrointestinal Motility;   Gastrointestinal Hormones;   Glucagon-Like Peptide 1;   Exendin (9-39)
Interventions: Drug: exendin(9-39)amide;   Drug: atropine
3 Completed Dose-response Study of Exendin-9,39 on Glucose Metabolism
Condition: Pancreatic Effects of 9,39-Exendin and 9,36-GLP-1
Interventions: Drug: saline infusion;   Drug: GLP-1-9,36 infusion;   Drug: Exendin-9,39 at low dose;   Drug: Exendin-9,39 at high dose
4 Recruiting Effect of Exendin-(9-39) On Glucose Requirements To Maintain Euglycemia
Condition: Congenital Hyperinsulinism
Intervention: Drug: Exendin-(9-39)
5 Recruiting Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
Condition: Congenital Hyperinsulinism
Interventions: Drug: Exendin-(9-39);   Drug: placebo
6 Recruiting Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Condition: Postprandial Hypoglycemia
Interventions: Drug: exendin-(9-39);   Other: placebo normal saline
7 Recruiting A Clinical Trial of Exendin-4 for the Treatment of Alzheimer's Disease
Condition: Alzheimer's Disease
Intervention: Drug: Exendin-4 (Exenatide)
8 Active, not recruiting Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism
Condition: Congenital Hyperinsulinism
Intervention: Drug: exendin-(9-39)
9 Unknown † Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients
Conditions: Hyperinsulinism;   Hypoglycemia;   Insulinoma
Intervention: Other: 111In-exendin-4 imaging
10 Completed Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Placebo tablet;   Drug: Sitagliptin tablet;   Drug: Saline infusion;   Drug: Exendin(9-39) infusion
11 Recruiting Ghrelin Effect on Beta Cell Function in Health and Disease
Condition: Diabetes
Interventions: Drug: Exendin (9-39);   Drug: acyl ghrelin;   Drug: saline
12 Recruiting The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Exendin 9, 39;   Drug: Placebo
13 Not yet recruiting Effect of GLP-1 on Postprandial Lipid Metabolism
Condition: Heart Disease
Interventions: Drug: Exendin-9;   Drug: GLP-1;   Other: saline
14 Active, not recruiting Exendin-4 as a Treatment for Parkinson's Disease - Pilot Study
Condition: Parkinson's Disease
Intervention: Drug: Exenatide
15 Recruiting GLP-1 Receptor Targeting in Diabetic and Healthy Individuals
Condition: Type 1 Diabetes
Intervention: Other: radiolabeled Exendin
16 Completed GLP-1 - Regulatory Mechanism of Postprandial Glycemia
Conditions: Healthy Subjects;   Gastric Emptying
Interventions: Drug: Saline;   Drug: Exendin(9-39)amide
17 Recruiting Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
Condition: Post-bariatric Surgery
Interventions: Drug: exendin-(9-39);   Drug: exendin -(9-39)
18 Suspended The Role of GLP-1 in Satiety Perception in Humans
Conditions: Appetite Regulation;   Obesity
Interventions: Drug: Exendin-(9-39) Acetate;   Drug: Saline 0.9%
19 Recruiting The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Exendin 9,39;   Drug: Placebo
20 Recruiting The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Obesity
Interventions: Drug: exenatide;   Drug: exenatide + exendin (9-39);   Drug: placebo
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† Indicates status has not been verified in more than two years