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90 studies found for:    chelation AND heart

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Rank Status Study
1 Completed Trial to Assess Chelation Therapy (TACT)
Condition: Coronary Artery Disease
Interventions: Drug: EDTA chelation therapy;   Drug: Placebo infusions
2 Completed Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major
Conditions: Iron Overload;   Cardiomyopathy
Interventions: Drug: Deferoxamine and Deferiprone;   Drug: Deferoxamine
3 Not yet recruiting An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Condition: Thalassemia, Non-transfusion Dependent Thalassemia, Myelodysplastic Syndromes, Myelofibrosis, Other Anemia
Intervention: Radiation: Single arm MRI test
4 Recruiting Safety and Efficacy of Deferasirox in β-thalassaemia Patients With Severe Cardiac Iron Overload
Conditions: Transfusion-dependent β-thalassemia Patients;   Cardiac Iron Overload
Interventions: Drug: Deferasirox;   Drug: Deferasirox + Deferoxamine
5 Completed Efficacy Study in Removing Excess Iron From the Heart
Conditions: Thalassemia Major;   Hemosiderosis
Interventions: Drug: Ferriprox (deferiprone);   Drug: Desferal (deferoxamine)
6 Active, not recruiting Cardiac Function in Patients With Hereditary Hemochromatosis
Condition: Hemochromatosis
Intervention:
7 Recruiting Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Condition: Thalassemia Major With Severe Transfusional Iron Overload
Intervention: Drug: Deferasirox and deferiprone
8 Completed Cardiac T2* in Beta-thalassemia Patients on Deferasirox Treatment
Conditions: Beta-thalassemia;   Iron Overload
Intervention: Drug: Deferasirox
9 Unknown † Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: deferiprone
10 Active, not recruiting Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron Overload
Conditions: Transfusional Iron Overload;   Transfusional Hemosiderosis
Interventions: Drug: Deferasirox;   Drug: Deferoxamine
11 Not yet recruiting Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
Condition: Acute Kidney Injury
Interventions: Drug: deferiprone;   Drug: Placebo
12 Unknown † Clinical Importance of Treating Iron Overload in Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Transfusion Hemochromatosis
Intervention: Drug: deferasirox
13 Unknown † Iron Balance Study of Deferasirox, Deferoxamine and the Combination of Both
Condition: Thalassemia
Interventions: Drug: Deferoxamine;   Drug: Deferasirox
14 Active, not recruiting Combo Chelation Trial
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Combo Chelation with Deferasirox (Exjade) and Desferal (DFO)
15 Completed Efficacy Study of the Use of Sequential DFP-DFO Versus DFP
Conditions: Beta-Thalassemia;   Thalassemia Major
Interventions: Drug: Deferiprone (DFP) and Deferoxamine (DFO);   Drug: Deferiprone (DFP)
16 Completed Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload
Conditions: Transfusional Iron Overload;   Beta-thalassemia
Intervention: Drug: SPD602 (FBS0701, SSP-004184)
17 Recruiting Myelodysplastic Syndromes (MDS) Event Free Survival With Iron Chelation Therapy Study
Condition: Myelodysplastic Syndromes
Interventions: Drug: Deferasirox;   Drug: Deferasirox placebo
18 Recruiting Screening for Subjects to Participate in Studies of Blood Disorders
Conditions: Bone Marrow Transplant;   Sickle Cell Disease
Intervention:
19 Completed Deferiprone for the Prevention of Contrast-Induced Acute Kidney Injury
Condition: Contrast-Induced Acute Kidney Injury
Interventions: Drug: CRMD-001-Deferiprone;   Drug: Placebo
20 Completed Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
Conditions: Anemia (Iron-Loading);   Beta-Thalassemia;   Hematologic Diseases;   Hemoglobinopathies;   Thalassemia;   Iron Overload
Intervention: Drug: chelation therapy
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† Indicates status has not been verified in more than two years