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31 studies found for:    aplastic anemia | Open Studies | NIH, U.S. Fed

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1 Recruiting Eltrombopag for Moderate Aplastic Anemia
Conditions: Eltrombopag;   Aplastic Anemia;   Aplastic Anemia Treatment;   Moderate Aplastic Anemia;   Moderate Aplastic Anemia Treatment
Intervention: Drug: Eltrombopag
2 Recruiting Alemtuzumab to Treat Severe Aplastic Anemia
Conditions: Relapsed or Refractory Severe Aplastic Anemia;   Severe Aplastic Anemia
Intervention: Drug: Alemtuzumab (Campath(Registered Trademark))
3 Recruiting Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome
Conditions: Myelodysplastic Syndrome (MDS);   Severe Aplastic Anemia (SAA)
Interventions: Other: Umbilical Cord Blood;   Other: Haploidentical Stem Cells;   Device: Miltenvi CliniMACs CD34 Reagent System
4 Recruiting Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia
Conditions: Aplastic Anemia;   Neutropenia;   Pancytopenia;   Anemia;   Thrombocytopenia
Interventions: Drug: Eltrombopag;   Drug: Horse Anti-Thymocyte Globulin (ATG);   Drug: Cyclosporine A (CSA)
5 Recruiting Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment
Conditions: Anemia, Aplastic;   Anemia, Hypoplastic
Interventions: Drug: h-ATG (ATGAM(Registered Trademark));   Drug: Cyclosporine (Gengraf(Registered Trademark))
6 Recruiting Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Conditions: Severe Aplastic Anemia;   MDS (Myelodysplastic Syndrome)
Interventions: Device: Miltenyi CD34 Reagent System;   Other: Donor derived G-CSF mobilized PBC
7 Recruiting A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Aplastic Anemia Patients With Immunosuppressive-Therapy Refractory Thrombocytopenia
Conditions: Anemia, Aplastic;   Anemia, Hypoplastic;   Thrombocytopenia
Interventions: Drug: Eltrombopag (Promacta);   Drug: Eltrombopag
8 Unknown † Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia
Condition: Anemia, Aplastic
Interventions: Drug: Sirolimus;   Drug: Cyclosporine
9 Recruiting Danazol for Genetic Bone Marrow and Lung Disorders
Condition: Aplastic Anemia
Intervention: Drug: Danazol
10 Recruiting Fludarabine-Based Conditioning for Allogeneic Marrow Transplantation in Aplastic Anemia
Condition: Aplastic Anemia
Interventions: Drug: Antithymocyte Globulin;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Radiation: Total Body Irradiation (TBI);   Procedure: Bone Marrow Transplant
11 Recruiting Fludarabine-based Conditioning for Severe Aplastic Anemia
Condition: Anemia, Aplastic
Intervention: Drug: Cyclophosphamide
12 Recruiting High-Tc Susceptometer to Monitor Transfusional Iron Overload
Conditions: Transfusional Iron Overload;   Thalassemia Major;   Sickle Cell Disease;   Myelodysplastic Syndromes;   Aplastic Anemia
Intervention: Device: Hepatic biomagnetic susceptibility measurement
13 Recruiting Transplants With Unlicensed Preserved Cord Blood
Conditions: Myelodysplastic Syndrome (MDS);   Hematologic Neoplasms;   Hematologic Diseases;   Severe Aplastic Anemia
Intervention: Procedure: Cord Blood Transplant
14 Recruiting Cancer in Inherited Bone Marrow Failure Syndromes
Conditions: Fanconi's Anemia;   Anemia, Diamond Blackfan;   Dyskeratosis Congenital;   Thrombocytopenia;   Neutropenia
Intervention:
15 Recruiting Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Conditions: Hematologic Disease;   Lymphoma;   Multiple Myeloma;   Myelodysplastic Syndrome;   Myeloproliferative Disorder
Intervention: Procedure: Stem cell transplantation
16 Recruiting Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Conditions: Chronic Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Lymphoproliferative Disorder;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms;   Nonmalignant Neoplasm
Interventions: Other: biologic sample preservation procedure;   Other: cytology specimen collection procedure
17 Recruiting Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
Condition: Healthy
Intervention:
18 Recruiting Identification of Viruses Associated With Diseases of Unknown Cause
Condition: Viral Diseases
Intervention:
19 Recruiting Radiation Therapy and the Natural History of Childhood Cancers
Condition: Neoplasms
Intervention:
20 Recruiting Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Conditions: Congenital Hemolytic Anemia;   Diamond-Blackfan Anemia
Interventions: Procedure: Radiotherapy;   Drug: Alemtuzumab (Campath(Registered Trademark));   Drug: Sirolimus (Rapamune(Registered Trademark))
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† Indicates status has not been verified in more than two years