118 studies found for:    abiraterone
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1 Completed A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants
Condition: Healthy
Interventions: Drug: Treatment A: abiraterone acetate;   Drug: Treatment B: abiraterone acetate;   Drug: Treatment C: abiraterone acetate
2 Completed A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet
Condition: Healthy Participants
Interventions: Drug: Abiraterone acetate, 250 mg (uncoated, current commercial tablet);   Drug: Abiraterone acetate, 500 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 250 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 500 mg (coated tablet, slower in vitro dissolution)
3 Completed A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men
Condition: Healthy Volunteers
Interventions: Drug: Period 1: Abiraterone;   Drug: Period 2: Abiraterone/Ketoconazole
4 Completed A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Abiraterone in Healthy Male Participants
Condition: Healthy
Interventions: Drug: Abiraterone acetate;   Drug: Rifampicin
5 Completed A Study to Assess the Effect of Timing of Food Intake on the Pharmacokinetics of Abiraterone Following Single-Dose Administration of Abiraterone Acetate Tablets in Healthy Caucasian and Japanese Men
Condition: Pharmacology
Interventions: Drug: Abiraterone: Treatment A;   Drug: Abiraterone: Treatment B;   Drug: Abiraterone: Treatment C;   Drug: Abiraterone: Treatment D
6 Active, not recruiting A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate
Condition: Prostate Cancer
Interventions: Drug: AT13387 and abiraterone;   Drug: AT13387 alone
7 Not yet recruiting Trial of Abiraterone Acetate Plus LHRH-therapy Versus Abiraterone Acetate Sparing LHRH-therapy in Patients With Progressive Chemotherapy-naïve Castration-resistant Prostate Cancer (SPARE)
Condition: Prostate Cancer
Interventions: Drug: abiraterone acetate + prednisone + LHRH-therapy;   Drug: abiraterone acetate + prednisone
8 Recruiting 3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy
Condition: Prostate Cancer
Interventions: Drug: Abiraterone acetate;   Drug: Abiraterone acetate plus degarelix;   Drug: Degarelix
9 Completed A Study to Assess the Effect of Abiraterone (JNJ-589485) on the Pharmacokinetics of Pioglitazone Following Administration of Abiraterone Acetate (JNJ-212082) and Pioglitazone HCl Tablets in Healthy Male Participants
Condition: Healthy Volunteers
Interventions: Drug: Pioglitazone HCl;   Drug: Abiraterone acetate
10 Completed
Has Results
Abiraterone Acetate Dose-Escalation Study in Hormone Refractory Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: prednisone/prednisolone or dexamethasone
11 Recruiting Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Condition: Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: Enzalutamide;   Drug: LHRHa
12 Not yet recruiting A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostatic Neoplasms;   Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: JNJ-56021927
13 Active, not recruiting A Study of Abiraterone Acetate Plus Prednisone With or Without Exemestane in Postmenopausal Women With Estrogen Receptor-Positive (ER+) Metastatic Breast Cancer Progressing After Letrozole or Anastrozole Therapy
Conditions: Metastatic ER+ Her2- Breast Cancer;   Postmenopausal
Interventions: Drug: Exemestane;   Drug: Abiraterone acetate + Prednisone/ Prednisolone + Exemestane;   Drug: Abiraterone acetate + Prednisone or Prednisolone
14 Recruiting Abiraterone Acetate for Castrate Resistant Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: Abiraterone;   Drug: Prednisone
15 Completed
Has Results
A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostate Neoplasms;   Prostate Cancer
Interventions: Drug: Abiraterone;   Drug: Prednisone
16 Completed A Study to Assess the Relative Bioavailability of 4 New Abiraterone Acetate Tablet Formulations With Respect to the Current Commercial Abiraterone Acetate Tablet Under Fasted Conditions in Healthy Male Participants
Condition: Healthy Volunteers
Interventions: Drug: Treatment A;   Drug: Treatment B;   Drug: Treatment C;   Drug: Treatment D;   Drug: Treatment E
17 Terminated A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer
Condition: Castrate-resistant Prostate Cancer Patients.
Interventions: Drug: BEZ235;   Drug: Prednisone;   Drug: Abiraterone acetate
18 Completed A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency
Condition: 21-hydroxylase Deficiency
Intervention: Drug: Abiraterone acetate
19 Recruiting A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Prednisone;   Other: Androgen deprivation therapy (ADT);   Drug: Abiraterone acetate Placebo;   Drug: Prednisone Placebo
20 Recruiting RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistant (The RESTORE Study)
Condition: Prostate Cancer
Interventions: Drug: Testosterone cypionate;   Drug: Testosterone Enanthate;   Drug: Abiraterone acetate;   Drug: Enzalutamide

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Indicates status has not been verified in more than two years