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84 studies found for:    abiraterone

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1 Completed A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants
Condition: Healthy
Interventions: Drug: Treatment A: abiraterone acetate;   Drug: Treatment B: abiraterone acetate;   Drug: Treatment C: abiraterone acetate
2 Completed A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet
Condition: Healthy Participants
Interventions: Drug: Abiraterone acetate, 250 mg (uncoated, current commercial tablet);   Drug: Abiraterone acetate, 500 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 250 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 500 mg (coated tablet, slower in vitro dissolution)
3 Completed A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men
Condition: Healthy Volunteers
Interventions: Drug: Period 1: Abiraterone;   Drug: Period 2: Abiraterone/Ketoconazole
4 Completed A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Abiraterone in Healthy Male Participants
Condition: Healthy
Interventions: Drug: Abiraterone acetate;   Drug: Rifampicin
5 Completed A Study to Assess the Effect of Timing of Food Intake on the Pharmacokinetics of Abiraterone Following Single-Dose Administration of Abiraterone Acetate Tablets in Healthy Caucasian and Japanese Men
Condition: Pharmacology
Interventions: Drug: Abiraterone: Treatment A;   Drug: Abiraterone: Treatment B;   Drug: Abiraterone: Treatment C;   Drug: Abiraterone: Treatment D
6 Recruiting A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate
Condition: Prostate Cancer
Interventions: Drug: AT13387 and abiraterone;   Drug: AT13387 alone
7 Recruiting 3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy
Condition: Prostate Cancer
Interventions: Drug: Abiraterone acetate;   Drug: Abiraterone acetate plus degarelix;   Drug: Degarelix
8 Recruiting A Study of Abiraterone Acetate Plus Prednisone With or Without Exemestane in Postmenopausal Women With Estrogen Receptor-Positive (ER+) Metastatic Breast Cancer Progressing After Letrozole or Anastrozole Therapy
Conditions: Metastatic ER+ Her2- Breast Cancer;   Postmenopausal
Interventions: Drug: Exemestane;   Drug: Abiraterone acetate + Prednisone/ Prednisolone + Exemestane;   Drug: Abiraterone acetate + Prednisone or Prednisolone
9 Not yet recruiting Phase II Study of ABT-263/Abiraterone or ABT-263/Abiraterone/Hydroxychloroquine in Prostrate Cancer
Condition: Castrate Refractory Prostate Cancer (CRPC)
Interventions: Drug: Abiraterone;   Drug: ABT-263;   Drug: Hydroxychloroquine
10 Recruiting A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer
Condition: Castrate-resistant Prostate Cancer Patients.
Interventions: Drug: BEZ235;   Drug: Prednisone;   Drug: Abiraterone acetate
11 Active, not recruiting A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency
Condition: 21-hydroxylase Deficiency
Intervention: Drug: Abiraterone acetate
12 Completed A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Prednisone;   Drug: Dextromethorphan hydrobromide;   Drug: Theophylline
13 Completed A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function
Condition: Renal Insufficiency
Interventions: Drug: Abiraterone acetate: participants with end-stage renal disease;   Drug: Abiraterone acetate: matched control participants with normal renal function
14 Completed A Pharmacokinetics Study to Assess Abiraterone Acetate Capsule and Tablet Formulations in Patients With Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Stage 1 Group 1: abiraterone acetate;   Drug: Stage 1 Group 2: abiraterone acetate;   Drug: Stage 2: abiraterone acetate;   Drug: Stage 3: abiraterone acetate;   Drug: Stage 3: glucocorticoid;   Drug: Stage 4: abiraterone acetate;   Drug: Stage 4: glucocorticoid
15 Completed A QT/QTc and Multi-Dose Pharmacokinetic Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Prednisone
16 Recruiting Abiraterone Acetate and Prednisone With or Without Veliparib in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Conditions: Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: abiraterone acetate;   Drug: prednisone;   Drug: veliparib;   Other: laboratory biomarker analysis
17 Not yet recruiting Alisertib, Abiraterone Acetate and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer;   Stage IV Prostate Cancer
Interventions: Drug: Alisertib;   Drug: Abiraterone acetate;   Drug: Prednisone
18 Completed Abiraterone Acetate in Patients With Prostate Cancer Who Have Failed Hormone Therapy
Condition: Prostate Neoplasms
Interventions: Drug: Phase 1: abiraterone acetate;   Drug: Phase 2: abiraterone acetate
19 Recruiting Abiraterone Acetate Trial in African American Prostate Cancer Patients
Condition: Prostate Cancer
Intervention: Drug: Abiraterone Acetate
20 Recruiting A Phase II Study of Increased-Dose Abiraterone Acetate in Patients With Castration Resistant Prostate Cancer
Condition: Castration Resistant Prostate Cancer
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone
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† Indicates status has not been verified in more than two years