123 studies found for:    abiraterone
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1 Completed A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants
Condition: Healthy
Interventions: Drug: Treatment A: abiraterone acetate;   Drug: Treatment B: abiraterone acetate;   Drug: Treatment C: abiraterone acetate
2 Completed A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Abiraterone in Healthy Male Participants
Condition: Healthy
Interventions: Drug: Abiraterone acetate;   Drug: Rifampicin
3 Not yet recruiting Bioequivalence Study of Abiraterone Acetate Coated and Uncoated Tablet Formulations in Healthy Male Participants
Condition: Healthy
Interventions: Drug: Abiraterone acetate (Treatment A);   Drug: Abiraterone acetate (Treatment B)
4 Completed
Has Results
Abiraterone Acetate Dose-Escalation Study in Hormone Refractory Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: prednisone/prednisolone or dexamethasone
5 Completed A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet
Condition: Healthy Participants
Interventions: Drug: Abiraterone acetate, 250 mg (uncoated, current commercial tablet);   Drug: Abiraterone acetate, 500 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 250 mg (coated, reformulated tablet);   Drug: Abiraterone acetate, 500 mg (coated tablet, slower in vitro dissolution)
6 Recruiting A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostatic Neoplasms;   Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: Drug: Abiraterone Acetate;   Drug: Prednisone;   Drug: JNJ-56021927
7 Completed A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency
Condition: 21-hydroxylase Deficiency
Intervention: Drug: Abiraterone acetate
8 Completed A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Abiraterone Following Administration of Abiraterone Acetate Tablets in Healthy Adult Men
Condition: Healthy Volunteers
Interventions: Drug: Period 1: Abiraterone;   Drug: Period 2: Abiraterone/Ketoconazole
9 Completed
Has Results
A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostate Neoplasms;   Prostate Cancer
Interventions: Drug: Abiraterone;   Drug: Prednisone
10 Active, not recruiting A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate
Condition: Prostate Cancer
Interventions: Drug: AT13387 and abiraterone;   Drug: AT13387 alone
11 Recruiting A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Prednisone;   Other: Androgen deprivation therapy (ADT);   Drug: Abiraterone acetate Placebo;   Drug: Prednisone Placebo
12 Recruiting RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistant (The RESTORE Study)
Condition: Prostate Cancer
Interventions: Drug: Testosterone cypionate;   Drug: Testosterone Enanthate;   Drug: Abiraterone acetate;   Drug: Enzalutamide
13 Recruiting Abiraterone Acetate for Castrate Resistant Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: Abiraterone;   Drug: Prednisone
14 Completed A Study to Assess the Effect of Timing of Food Intake on the Pharmacokinetics of Abiraterone Following Single-Dose Administration of Abiraterone Acetate Tablets in Healthy Caucasian and Japanese Men
Condition: Pharmacology
Interventions: Drug: Abiraterone: Treatment A;   Drug: Abiraterone: Treatment B;   Drug: Abiraterone: Treatment C;   Drug: Abiraterone: Treatment D
15 Completed A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer
Condition: Prostate Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Prednisone;   Drug: Dextromethorphan hydrobromide;   Drug: Theophylline
16 Completed
Has Results
A Safety and Efficacy Study of Abiraterone Acetate in Participants With Prostate Cancer Who Have Failed Hormone Therapy
Condition: Prostatic Neoplasms
Interventions: Drug: Abiraterone acetate;   Drug: Abiraterone acetate MTD;   Drug: Dexamethasone
17 Active, not recruiting A Study of Abiraterone Acetate Plus Prednisone With or Without Exemestane in Postmenopausal Women With Estrogen Receptor-Positive (ER+) Metastatic Breast Cancer Progressing After Letrozole or Anastrozole Therapy
Conditions: Metastatic ER+ Her2- Breast Cancer;   Postmenopausal
Interventions: Drug: Exemestane;   Drug: Abiraterone acetate + Prednisone/ Prednisolone + Exemestane;   Drug: Abiraterone acetate + Prednisone or Prednisolone
18 Terminated A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer
Condition: Castrate-resistant Prostate Cancer Patients.
Interventions: Drug: BEZ235;   Drug: Prednisone;   Drug: Abiraterone acetate
19 Recruiting Abiraterone Acetate Trial in African American Prostate Cancer Patients
Condition: Prostate Cancer
Intervention: Drug: Abiraterone Acetate
20 Completed A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function
Condition: Renal Insufficiency
Interventions: Drug: Abiraterone acetate: participants with end-stage renal disease;   Drug: Abiraterone acetate: matched control participants with normal renal function

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