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14 studies found for:    TRPV4
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Rank Status Study
1 Recruiting A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure
Condition: Heart Failure, Congestive
Interventions: Procedure: DCE-MRI scans;   Other: Gadobutrol
2 Recruiting A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
Condition: Oedema, Pulmonary
Interventions: Drug: GSK2798745 solution;   Drug: GSK2798745 suspension;   Drug: GSK2798745 capsule;   Drug: Placebo solution;   Drug: Placebo suspension;   Drug: Placebo capsule
3 Recruiting Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel
Condition: Cancer
Intervention: Drug: SOR-C13
4 Completed Use Of SB-705498 In The Acute Treatment Of Migraine
Condition: Migraine, Acute
Intervention: Drug: SB-705498
5 Completed Human Safety of Capsaicin Inhalation Challenge Testing for Young and Older Men
Condition: COPD
Intervention: Biological: biological/vaccine
6 Recruiting TRPV Expression in Subjects With Sensitive Skin
Condition: Sensitive Skin
Interventions: Procedure: Skin biopsy;   Procedure: Oral mucosa specimen
7 Completed Onabotulinumtoxina Intradetrusorial Injections and NGF Expression
Conditions: Overactive Detrusor;   Detrusor Hyperreflexia of Bladder
8 Recruiting Bronchial Thermoplasty: Effect on Neuronal and Chemosensitive Component of the Bronchial Mucosa
Condition: Severe Persistent Asthma
Intervention: Device: catheter ALAIR
9 Completed Cumulative Irritation Test of PAC-14028 in Healthy Volunteers
Condition: Healthy
Interventions: Other: PAC14028-Vehicle;   Drug: PAC14028-0.1;   Drug: PAC14028-0.3;   Drug: PAC14028-1.0;   Other: Saline;   Other: Positive
10 Recruiting Civamide Nasal Solution for Postherpetic Neuralgia of the Trigeminal Nerve
Condition: Postherpetic Neuralgia
Interventions: Drug: Civamide Nasal Spray;   Drug: Placebo
11 Completed SB705498 Proof of Concept Chamber Challenge in Subjects With Non Allergic Rhinitis
Conditions: Non-allergic Rhinitis;   Rhinitis
Interventions: Drug: SB-705498;   Drug: Placebo
12 Recruiting A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With Chronic Idiopathic Cough
Condition: Chronic Idiopathic Cough
Interventions: Drug: XEN-D0501;   Drug: Placebo
13 Recruiting A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: XEN-D0501;   Drug: Placebo
14 Completed Efficacy and Safety Study of PAC-14028 Cream in Dermal Pruritus
Condition: Skin Pruritus
Interventions: Drug: PAC-14028;   Other: Vehicle

Indicates status has not been verified in more than two years