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8 studies found for:    SMAD4
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Rank Status Study
1 Active, not recruiting High-Dose Radiation Therapy Versus Standard Care in Treating Patients With Pancreatic Cancer That Cannot Be Removed By Surgery
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Duct Cell Adenocarcinoma of the Pancreas;   Stage III Pancreatic Cancer
Interventions: Drug: gemcitabine hydrochloride;   Drug: oxaliplatin;   Drug: irinotecan hydrochloride;   Drug: leucovorin calcium;   Drug: fluorouracil;   Radiation: intensity-modulated radiation therapy;   Radiation: 3-dimensional conformal radiation therapy;   Drug: capecitabine;   Other: laboratory biomarker analysis
2 Unknown  French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis
Condition: Quality of Life
Interventions: Other: Procedure surgery behavioral and genetic diagnosis;   Procedure: quality of life after different type of surgery
3 Not yet recruiting MR Guided Dose Escalated RT + Concurrent Chemotherapy in Unresectable Pancreatic Cancer
Condition: Unresectable Pancreatic Cancer
Interventions: Radiation: Radiation Therapy;   Drug: Concurrent chemotherapy (Gemcitabine, Capecitabine)
4 Not yet recruiting Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer
Condition: Borderline Resectable Pancreatic Cancer
Interventions: Drug: gemcitabine/nab-paclitaxel;   Drug: mFOLFIRINOX
5 Recruiting Curative Efficacy of Pravastatine in Patients Presented Delayed Cutaneous and Subcutaneous Radio-induced Fibrosis
Condition: Fibrosis
Intervention: Drug: Pravastatin
6 Completed Tolerability and Bioavailability of the P144 Peptide Inhibitor of TGF-β1 After Topical Administration in Healthy Volunteers
Condition: Healthy
Interventions: Drug: P144 cream;   Drug: Placebo
7 Recruiting First in Human Dose Escalation Study of TEW-7197 in Subjects With Advanced Stage Solid Tumors
Condition: Advanced Stage Solid Tumors
Intervention: Drug: TEW-7197
8 Completed Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis
Condition: Skin Fibrosis
Interventions: Drug: P144;   Drug: placebo

Indicates status has not been verified in more than two years